PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Nicotiana benthamiana
SRS Family
Species TF ID Description
Niben101Scf00158g06008.1SRS family protein
Niben101Scf00197g03004.1SRS family protein
Niben101Scf00383g00001.1SRS family protein
Niben101Scf01025g13019.1SRS family protein
Niben101Scf01190g00013.1SRS family protein
Niben101Scf02864g03015.1SRS family protein
Niben101Scf04190g00008.1SRS family protein
Niben101Scf04664g04022.1SRS family protein
Niben101Scf05201g11005.1SRS family protein
Niben101Scf06228g01001.1SRS family protein
Niben101Scf06752g02003.1SRS family protein
Niben101Scf07034g01002.1SRS family protein
Niben101Scf08273g05002.1SRS family protein
Niben101Scf14083g01010.1SRS family protein
Niben101Scf20652g01005.1SRS family protein
Niben101Scf20652g01023.1SRS family protein
Niben101Scf21969g00004.1SRS family protein
SRS Family Introduction

SHI RELATED SEQUENCE(SRS), which encode proteins with a single zinc finger motif. The genes are members of a small gene family of putative transcription factors in which the SHORT INTERNODES (SHI) gene is found.

The predicted amino acid sequence of SHI has acidic and glutamine-rich stretches and shows sequence similarity over a putative zinc finger region to three presumptive Arabidopsis proteins. This suggests that SHI may act as a negative regulator of GA responses through transcriptional control.

The predicted SHI protein consists of 331 amino acids. A region containing six cysteine residues (amino acids 120 to 147) in a C-X2-C-X7-C-X4-C-X2-C-X7-C arrangement (where X is a variable amino acid) is suggested to make up a zinc finger domain similar to the Zn2Cys6 cluster found in the DNA binding region of the yeast transcriptional activator GAL4 (Kraulis et al. 1992 ). Two regions rich in glutamine residues were found adjacent to the zinc finger domain, as well as a short stretch of acidic residues in the C-terminal third of the SHI protein. These features have been found in transcription factor proteins and have been demonstrated to be important for their function as transcriptional activators (Mitchell and Tjian 1989 ). Furthermore, two putative nuclear localization signals (NLSs) were found in the SHI sequence. These are two basic stretches (amino acids 160 to 165 and 183 to 188) that conform to the consensus of the simian virus 40ĘClike "typical NLS" defined as four arginines and lysines within a region of six amino acids (Boulikas 1994 ; LaCasse and Lefebvre 1995 ).

Fridborg I, Kuusk S, Moritz T, Sundberg E.
The Arabidopsis dwarf mutant shi exhibits reduced gibberellin responses conferred by overexpression of a new putative zinc finger protein.
Plant Cell. 1999 Jun;11(6):1019-32.
PMID:10368174