PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Nicotiana benthamiana
ERF Family
Species TF ID Description
Niben101Ctg00054g00001.1ERF family protein
Niben101Ctg04506g00002.1ERF family protein
Niben101Ctg12291g00001.1ERF family protein
Niben101Ctg13994g00001.1ERF family protein
Niben101Ctg14204g00003.1ERF family protein
Niben101Ctg15010g00002.1ERF family protein
Niben101Ctg15705g00001.1ERF family protein
Niben101Ctg15705g00004.1ERF family protein
Niben101Ctg16023g00001.1ERF family protein
Niben101Ctg16385g00003.1ERF family protein
Niben101Scf00085g00008.1ERF family protein
Niben101Scf00113g03002.1ERF family protein
Niben101Scf00163g22002.1ERF family protein
Niben101Scf00163g22003.1ERF family protein
Niben101Scf00163g22004.1ERF family protein
Niben101Scf00177g02016.1ERF family protein
Niben101Scf00262g04006.1ERF family protein
Niben101Scf00278g05001.1ERF family protein
Niben101Scf00282g02006.1ERF family protein
Niben101Scf00298g00001.1ERF family protein
Niben101Scf00315g02001.1ERF family protein
Niben101Scf00428g09009.1ERF family protein
Niben101Scf00428g10006.1ERF family protein
Niben101Scf00454g02007.1ERF family protein
Niben101Scf00454g02008.1ERF family protein
Niben101Scf00454g03001.1ERF family protein
Niben101Scf00454g04003.1ERF family protein
Niben101Scf00503g07005.1ERF family protein
Niben101Scf00530g01001.1ERF family protein
Niben101Scf00546g00002.1ERF family protein
Niben101Scf00577g11004.1ERF family protein
Niben101Scf00603g02001.1ERF family protein
Niben101Scf00725g02012.1ERF family protein
Niben101Scf00753g02005.1ERF family protein
Niben101Scf00784g01003.1ERF family protein
Niben101Scf00839g00006.1ERF family protein
Niben101Scf00846g02001.1ERF family protein
Niben101Scf00870g05003.1ERF family protein
Niben101Scf00941g00007.1ERF family protein
Niben101Scf01001g06011.1ERF family protein
Niben101Scf01008g00004.1ERF family protein
Niben101Scf01075g01003.1ERF family protein
Niben101Scf01082g04001.1ERF family protein
Niben101Scf01082g07003.1ERF family protein
Niben101Scf01085g03003.1ERF family protein
Niben101Scf01090g02001.1ERF family protein
Niben101Scf01094g03014.1ERF family protein
Niben101Scf01094g03016.1ERF family protein
Niben101Scf01111g02001.1ERF family protein
Niben101Scf01142g04009.1ERF family protein
Niben101Scf01159g00002.1ERF family protein
Niben101Scf01177g01001.1ERF family protein
Niben101Scf01177g04031.1ERF family protein
Niben101Scf01212g03003.1ERF family protein
Niben101Scf01212g03005.1ERF family protein
Niben101Scf01237g06003.1ERF family protein
Niben101Scf01295g05006.1ERF family protein
Niben101Scf01297g01001.1ERF family protein
Niben101Scf01374g05001.1ERF family protein
Niben101Scf01426g00001.1ERF family protein
Niben101Scf01430g00007.1ERF family protein
Niben101Scf01453g11005.1ERF family protein
Niben101Scf01518g08004.1ERF family protein
Niben101Scf01539g00001.1ERF family protein
Niben101Scf01543g03001.1ERF family protein
Niben101Scf01611g11002.1ERF family protein
Niben101Scf01669g04022.1ERF family protein
Niben101Scf01692g03007.1ERF family protein
Niben101Scf01695g01005.1ERF family protein
Niben101Scf01701g03007.1ERF family protein
Niben101Scf01752g05003.1ERF family protein
Niben101Scf01767g03004.1ERF family protein
Niben101Scf01795g06002.1ERF family protein
Niben101Scf01817g01001.1ERF family protein
Niben101Scf01818g07006.1ERF family protein
Niben101Scf01818g08019.1ERF family protein
Niben101Scf01942g08004.1ERF family protein
Niben101Scf01947g01008.1ERF family protein
Niben101Scf01956g05006.1ERF family protein
Niben101Scf01956g10015.1ERF family protein
Niben101Scf01956g12014.1ERF family protein
Niben101Scf01956g12018.1ERF family protein
Niben101Scf01980g04003.1ERF family protein
Niben101Scf02063g05001.1ERF family protein
Niben101Scf02182g19004.1ERF family protein
Niben101Scf02182g21007.1ERF family protein
Niben101Scf02219g02002.1ERF family protein
Niben101Scf02242g03012.1ERF family protein
Niben101Scf02316g03001.1ERF family protein
Niben101Scf02397g00007.1ERF family protein
Niben101Scf02408g00021.1ERF family protein
Niben101Scf02437g08005.1ERF family protein
Niben101Scf02475g08017.1ERF family protein
Niben101Scf02483g02007.1ERF family protein
Niben101Scf02543g00002.1ERF family protein
Niben101Scf02577g03014.1ERF family protein
Niben101Scf02720g08001.1ERF family protein
Niben101Scf02744g00004.1ERF family protein
Niben101Scf02775g00001.1ERF family protein
Niben101Scf02775g00002.1ERF family protein
Niben101Scf02775g00003.1ERF family protein
Niben101Scf02972g00008.1ERF family protein
Niben101Scf03035g01006.1ERF family protein
Niben101Scf03045g14001.1ERF family protein
Niben101Scf03092g00007.1ERF family protein
Niben101Scf03202g13015.1ERF family protein
Niben101Scf03223g00002.1ERF family protein
Niben101Scf03245g04004.1ERF family protein
Niben101Scf03245g04005.1ERF family protein
Niben101Scf03245g06003.1ERF family protein
Niben101Scf03310g00003.1ERF family protein
Niben101Scf03314g00004.1ERF family protein
Niben101Scf03321g01009.1ERF family protein
Niben101Scf03479g03001.1ERF family protein
Niben101Scf03510g06011.1ERF family protein
Niben101Scf03548g02037.1ERF family protein
Niben101Scf03580g01003.1ERF family protein
Niben101Scf03657g02001.1ERF family protein
Niben101Scf03732g03003.1ERF family protein
Niben101Scf03772g00001.1ERF family protein
Niben101Scf03773g00009.1ERF family protein
Niben101Scf03850g01005.1ERF family protein
Niben101Scf03930g01015.1ERF family protein
Niben101Scf03985g01005.1ERF family protein
Niben101Scf04131g01007.1ERF family protein
Niben101Scf04131g01028.1ERF family protein
Niben101Scf04217g07002.1ERF family protein
Niben101Scf04337g01005.1ERF family protein
Niben101Scf04350g04004.1ERF family protein
Niben101Scf04437g00010.1ERF family protein
Niben101Scf04505g02007.1ERF family protein
Niben101Scf04634g00008.1ERF family protein
Niben101Scf04763g00013.1ERF family protein
Niben101Scf04763g00014.1ERF family protein
Niben101Scf04826g01005.1ERF family protein
Niben101Scf04860g02011.1ERF family protein
Niben101Scf05123g02008.1ERF family protein
Niben101Scf05135g06001.1ERF family protein
Niben101Scf05140g01007.1ERF family protein
Niben101Scf05156g01011.1ERF family protein
Niben101Scf05173g07004.1ERF family protein
Niben101Scf05173g07005.1ERF family protein
Niben101Scf05173g08002.1ERF family protein
Niben101Scf05173g08003.1ERF family protein
Niben101Scf05173g09004.1ERF family protein
Niben101Scf05357g00008.1ERF family protein
Niben101Scf05440g02002.1ERF family protein
Niben101Scf05459g00001.1ERF family protein
Niben101Scf05480g00003.1ERF family protein
Niben101Scf05618g01002.1ERF family protein
Niben101Scf05692g06003.1ERF family protein
Niben101Scf05773g00002.1ERF family protein
Niben101Scf05800g00005.1ERF family protein
Niben101Scf05827g07015.1ERF family protein
Niben101Scf05849g00002.1ERF family protein
Niben101Scf05855g00002.1ERF family protein
Niben101Scf05855g06014.1ERF family protein
Niben101Scf05993g01013.1ERF family protein
Niben101Scf06026g00002.1ERF family protein
Niben101Scf06081g02026.1ERF family protein
Niben101Scf06117g01012.1ERF family protein
Niben101Scf06119g02002.1ERF family protein
Niben101Scf06120g00005.1ERF family protein
Niben101Scf06157g01005.1ERF family protein
Niben101Scf06190g06004.1ERF family protein
Niben101Scf06200g00001.1ERF family protein
Niben101Scf06200g01006.1ERF family protein
Niben101Scf06328g00004.1ERF family protein
Niben101Scf06348g00034.1ERF family protein
Niben101Scf06378g04004.1ERF family protein
Niben101Scf06413g01001.1ERF family protein
Niben101Scf06413g01002.1ERF family protein
Niben101Scf06413g02012.1ERF family protein
Niben101Scf06436g05001.1ERF family protein
Niben101Scf06444g02001.1ERF family protein
Niben101Scf06473g01014.1ERF family protein
Niben101Scf06596g03021.1ERF family protein
Niben101Scf06621g02032.1ERF family protein
Niben101Scf06848g08006.1ERF family protein
Niben101Scf06848g09002.1ERF family protein
Niben101Scf06865g00004.1ERF family protein
Niben101Scf06913g00001.1ERF family protein
Niben101Scf06951g00004.1ERF family protein
Niben101Scf06969g00003.1ERF family protein
Niben101Scf06984g02002.1ERF family protein
Niben101Scf07066g03005.1ERF family protein
Niben101Scf07105g04007.1ERF family protein
Niben101Scf07172g00019.1ERF family protein
Niben101Scf07226g08005.1ERF family protein
Niben101Scf07310g01001.1ERF family protein
Niben101Scf07579g01012.1ERF family protein
Niben101Scf07693g00011.1ERF family protein
Niben101Scf07761g00004.1ERF family protein
Niben101Scf07761g00005.1ERF family protein
Niben101Scf07761g02006.1ERF family protein
Niben101Scf07896g01006.1ERF family protein
Niben101Scf07913g00005.1ERF family protein
Niben101Scf07926g07004.1ERF family protein
Niben101Scf08033g01007.1ERF family protein
Niben101Scf08050g00012.1ERF family protein
Niben101Scf08060g00005.1ERF family protein
Niben101Scf08141g01011.1ERF family protein
Niben101Scf08196g00012.1ERF family protein
Niben101Scf08249g02004.1ERF family protein
Niben101Scf08278g00007.1ERF family protein
Niben101Scf08516g01005.1ERF family protein
Niben101Scf08546g00001.1ERF family protein
Niben101Scf08546g03002.1ERF family protein
Niben101Scf08546g05002.1ERF family protein
Niben101Scf08546g05004.1ERF family protein
Niben101Scf08546g05005.1ERF family protein
Niben101Scf08597g01023.1ERF family protein
Niben101Scf08651g04017.1ERF family protein
Niben101Scf08776g00003.1ERF family protein
Niben101Scf08840g00003.1ERF family protein
Niben101Scf08965g00003.1ERF family protein
Niben101Scf09004g00001.1ERF family protein
Niben101Scf09004g00003.1ERF family protein
Niben101Scf09087g00009.1ERF family protein
Niben101Scf09191g00005.1ERF family protein
Niben101Scf09236g00001.1ERF family protein
Niben101Scf09459g02008.1ERF family protein
Niben101Scf09659g03018.1ERF family protein
Niben101Scf09704g02001.1ERF family protein
Niben101Scf09882g01001.1ERF family protein
Niben101Scf10169g00004.1ERF family protein
Niben101Scf10283g01004.1ERF family protein
Niben101Scf10438g00009.1ERF family protein
Niben101Scf10438g00010.1ERF family protein
Niben101Scf10763g00021.1ERF family protein
Niben101Scf10785g01002.1ERF family protein
Niben101Scf10785g01014.1ERF family protein
Niben101Scf11303g01019.1ERF family protein
Niben101Scf11341g00009.1ERF family protein
Niben101Scf11424g01001.1ERF family protein
Niben101Scf11694g01005.1ERF family protein
Niben101Scf11706g00010.1ERF family protein
Niben101Scf11954g01002.1ERF family protein
Niben101Scf12210g07001.1ERF family protein
Niben101Scf12210g08011.1ERF family protein
Niben101Scf12483g01009.1ERF family protein
Niben101Scf12639g00001.1ERF family protein
Niben101Scf12874g00001.1ERF family protein
Niben101Scf13455g01002.1ERF family protein
Niben101Scf13695g01014.1ERF family protein
Niben101Scf13779g00003.1ERF family protein
Niben101Scf15451g00001.1ERF family protein
Niben101Scf15704g00006.1ERF family protein
Niben101Scf15962g00025.1ERF family protein
Niben101Scf15963g01004.1ERF family protein
Niben101Scf16007g00010.1ERF family protein
Niben101Scf16007g00011.1ERF family protein
Niben101Scf16506g00004.1ERF family protein
Niben101Scf17051g00007.1ERF family protein
Niben101Scf17204g01001.1ERF family protein
Niben101Scf17204g01003.1ERF family protein
Niben101Scf18347g00023.1ERF family protein
Niben101Scf19057g00005.1ERF family protein
Niben101Scf19091g00016.1ERF family protein
Niben101Scf19266g00006.1ERF family protein
Niben101Scf19266g01015.1ERF family protein
Niben101Scf19733g00001.1ERF family protein
Niben101Scf23241g00003.1ERF family protein
Niben101Scf34675g00005.1ERF family protein
Niben101Scf36372g00002.1ERF family protein
Niben101Scf36703g00001.1ERF family protein
ERF Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

After finding the tobacco ERFs, many proteins in the ERF family were identified and implicated in many diverse functions in cellular processes, such as hormonal signal transduction, response to biotic and abiotic stresses, regulation of metabolism, and in developmental processes in various plant species.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444


The first class are proteins which bind to ethylene response elements (ERE) or GCC boxes (tobacco EREBPs, Arabidopsis AtEBP and AtERF1-5, and tomato Pti4-6) found in the promoters of ethylene-inducible pathogenesis related genes. The GCC box is an 11 bp sequence (TAAGAGCCGCC) with a core GCCGCC sequence that is required for binding.
The second class includes proteins that bind to the C-repeat or dehydration response element (DRE) in the promoters of genes that are turned on in response to low temperatures and/or water deficit (CBF1, CBF2, CBF3/DREB1A and DREB2A). The C-repeat/DREs contain the core sequence CCGAC.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102