PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Medicago truncatula
WRKY Family
Species TF ID Description
Medtr0002s1250.1WRKY family protein
Medtr0117s0040.1WRKY family protein
Medtr0130s0060.1WRKY family protein
Medtr1g009613.1WRKY family protein
Medtr1g013760.1WRKY family protein
Medtr1g013790.1WRKY family protein
Medtr1g015140.1WRKY family protein
Medtr1g070455.1WRKY family protein
Medtr1g070455.2WRKY family protein
Medtr1g077760.1WRKY family protein
Medtr1g077780.1WRKY family protein
Medtr1g078260.1WRKY family protein
Medtr1g086790.1WRKY family protein
Medtr1g099600.1WRKY family protein
Medtr2g016770.1WRKY family protein
Medtr2g016770.2WRKY family protein
Medtr2g023930.1WRKY family protein
Medtr2g024350.1WRKY family protein
Medtr2g024380.1WRKY family protein
Medtr2g032030.1WRKY family protein
Medtr2g032030.2WRKY family protein
Medtr2g033820.1WRKY family protein
Medtr2g045360.1WRKY family protein
Medtr2g075610.1WRKY family protein
Medtr2g075680.1WRKY family protein
Medtr2g075690.1WRKY family protein
Medtr2g075700.1WRKY family protein
Medtr2g075750.1WRKY family protein
Medtr2g083870.1WRKY family protein
Medtr2g088000.1WRKY family protein
Medtr2g105060.1WRKY family protein
Medtr2g105060.2WRKY family protein
Medtr3g009470.1WRKY family protein
Medtr3g009470.2WRKY family protein
Medtr3g009470.3WRKY family protein
Medtr3g031220.1WRKY family protein
Medtr3g031220.2WRKY family protein
Medtr3g053330.1WRKY family protein
Medtr3g056100.1WRKY family protein
Medtr3g056100.2WRKY family protein
Medtr3g056100.3WRKY family protein
Medtr3g056100.4WRKY family protein
Medtr3g056100.5WRKY family protein
Medtr3g090860.1WRKY family protein
Medtr3g093830.1WRKY family protein
Medtr3g095040.1WRKY family protein
Medtr3g095080.1WRKY family protein
Medtr3g095080.2WRKY family protein
Medtr3g095080.3WRKY family protein
Medtr3g104750.1WRKY family protein
Medtr3g106060.1WRKY family protein
Medtr3g108960.1WRKY family protein
Medtr4g007060.1WRKY family protein
Medtr4g007060.2WRKY family protein
Medtr4g007060.3WRKY family protein
Medtr4g013260.1WRKY family protein
Medtr4g021780.1WRKY family protein
Medtr4g047580.1WRKY family protein
Medtr4g049760.1WRKY family protein
Medtr4g049790.1WRKY family protein
Medtr4g052030.1WRKY family protein
Medtr4g082580.1WRKY family protein
Medtr4g094412.1WRKY family protein
Medtr4g094412.2WRKY family protein
Medtr4g094412.3WRKY family protein
Medtr4g094412.4WRKY family protein
Medtr4g094588.1WRKY family protein
Medtr4g094908.1WRKY family protein
Medtr4g107970.1WRKY family protein
Medtr4g107970.2WRKY family protein
Medtr4g122530.1WRKY family protein
Medtr4g127040.1WRKY family protein
Medtr4g130900.1WRKY family protein
Medtr4g132430.1WRKY family protein
Medtr4g132430.2WRKY family protein
Medtr5g016610.1WRKY family protein
Medtr5g018380.1WRKY family protein
Medtr5g029850.1WRKY family protein
Medtr5g042920.1WRKY family protein
Medtr5g043880.1WRKY family protein
Medtr5g044695.2WRKY family protein
Medtr5g044695.3WRKY family protein
Medtr5g067680.1WRKY family protein
Medtr5g067700.1WRKY family protein
Medtr5g073620.1WRKY family protein
Medtr5g074200.1WRKY family protein
Medtr5g074400.1WRKY family protein
Medtr5g091390.1WRKY family protein
Medtr5g093540.1WRKY family protein
Medtr5g094430.1WRKY family protein
Medtr5g094430.2WRKY family protein
Medtr5g094430.3WRKY family protein
Medtr5g094430.4WRKY family protein
Medtr5g097490.1WRKY family protein
Medtr5g097490.2WRKY family protein
Medtr5g097490.3WRKY family protein
Medtr5g097500.1WRKY family protein
Medtr6g038890.1WRKY family protein
Medtr6g046600.1WRKY family protein
Medtr6g053200.1WRKY family protein
Medtr6g086555.1WRKY family protein
Medtr7g009730.1WRKY family protein
Medtr7g011820.1WRKY family protein
Medtr7g028415.1WRKY family protein
Medtr7g028710.1WRKY family protein
Medtr7g062220.1WRKY family protein
Medtr7g071120.1WRKY family protein
Medtr7g073380.1WRKY family protein
Medtr7g073430.1WRKY family protein
Medtr7g079010.1WRKY family protein
Medtr7g079040.1WRKY family protein
Medtr7g080000.1WRKY family protein
Medtr7g080020.1WRKY family protein
Medtr7g100510.1WRKY family protein
Medtr7g104980.1WRKY family protein
Medtr7g105000.1WRKY family protein
Medtr7g109600.1WRKY family protein
Medtr7g109600.2WRKY family protein
Medtr7g109800.1WRKY family protein
Medtr7g110720.1WRKY family protein
Medtr7g110720.2WRKY family protein
Medtr7g117200.1WRKY family protein
Medtr8g005750.1WRKY family protein
Medtr8g007270.1WRKY family protein
Medtr8g027860.1WRKY family protein
Medtr8g028565.1WRKY family protein
Medtr8g032510.1WRKY family protein
Medtr8g067635.1WRKY family protein
Medtr8g067650.1WRKY family protein
Medtr8g069935.1WRKY family protein
Medtr8g087000.1WRKY family protein
Medtr8g087000.2WRKY family protein
Medtr8g087000.3WRKY family protein
Medtr8g087000.4WRKY family protein
Medtr8g092010.1WRKY family protein
Medtr8g092010.2WRKY family protein
Medtr8g092140.1WRKY family protein
Medtr8g096730.1WRKY family protein
Medtr8g098945.1WRKY family protein
Medtr8g099350.1WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701