PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Medicago truncatula
TCP Family
Species TF ID Description
Medtr1g038650.1TCP family protein
Medtr1g038650.2TCP family protein
Medtr1g063870.1TCP family protein
Medtr1g101810.1TCP family protein
Medtr1g101810.2TCP family protein
Medtr1g101810.3TCP family protein
Medtr1g101810.4TCP family protein
Medtr1g103380.1TCP family protein
Medtr1g114380.1TCP family protein
Medtr2g006150.1TCP family protein
Medtr2g006150.2TCP family protein
Medtr2g078200.1TCP family protein
Medtr2g090960.1TCP family protein
Medtr2g090960.2TCP family protein
Medtr3g026050.1TCP family protein
Medtr4g079580.1TCP family protein
Medtr4g108370.1TCP family protein
Medtr4g109660.1TCP family protein
Medtr4g111935.1TCP family protein
Medtr5g039600.1TCP family protein
Medtr6g015350.1TCP family protein
Medtr6g017055.1TCP family protein
Medtr7g015010.1TCP family protein
Medtr7g018500.1TCP family protein
Medtr7g028160.1TCP family protein
Medtr8g033070.1TCP family protein
Medtr8g463380.1TCP family protein
TCP Family Introduction

The TCP gene family was first described in 1999, as a small group of plant genes encoding proteins sharing the socalled TCP domain, a 59-amino acid basic helix-loop-helix (bHLH) motif that allows DNA binding and protein-protein interactions. This domain was initially identified in four proteins encoded by apparently unrelated genes, from which the name 'TCP' was derived: teosinte branched1 (tb1) from maize (Zea mays), CYCLOIDEA (CYC) from snapdragon (Antirrhinum majus), and the PROLIFERATING CELL FACTORS 1 and 2 (PCF1 and PCF2) from rice (Oryza sativa). The tb1 gene is a major determinant of strong apical dominance in domesticated maize. CYC is involved in the control of floral bilateral symmetry in Antirrhinum. PCF1 and PCF2 are factors that bind to the promoter of the rice PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) gene, which encodes a protein involved in DNA replication and repair, maintenance of chromatin structure, chromosome segregation and cell-cycle progression.

TCP genes have been found in various plant species, and new roles in plant development have been elucidated. These discoveries emphasize the importance of this plant-specific gene family in the evolution and developmental control of plant form.

Martin-Trillo M, Cubas P.
TCP genes: a family snapshot ten years later.
Trends Plant Sci, 2010. 15(1): p. 31-9.
PMID: 19963426