PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Medicago truncatula
ERF Family
Species TF ID Description
Medtr0939s0010.1ERF family protein
Medtr0939s0010.2ERF family protein
Medtr1g006660.1ERF family protein
Medtr1g012470.1ERF family protein
Medtr1g014780.1ERF family protein
Medtr1g014800.1ERF family protein
Medtr1g014820.1ERF family protein
Medtr1g014860.1ERF family protein
Medtr1g019110.1ERF family protein
Medtr1g023170.1ERF family protein
Medtr1g028560.1ERF family protein
Medtr1g040430.1ERF family protein
Medtr1g043350.1ERF family protein
Medtr1g048610.1ERF family protein
Medtr1g058800.1ERF family protein
Medtr1g069940.1ERF family protein
Medtr1g069945.1ERF family protein
Medtr1g069960.1ERF family protein
Medtr1g069985.1ERF family protein
Medtr1g070000.1ERF family protein
Medtr1g070015.1ERF family protein
Medtr1g070020.1ERF family protein
Medtr1g070035.1ERF family protein
Medtr1g070045.1ERF family protein
Medtr1g070070.1ERF family protein
Medtr1g074230.1ERF family protein
Medtr1g074250.1ERF family protein
Medtr1g074260.1ERF family protein
Medtr1g074270.1ERF family protein
Medtr1g074280.1ERF family protein
Medtr1g074290.1ERF family protein
Medtr1g074310.1ERF family protein
Medtr1g074370.1ERF family protein
Medtr1g079630.1ERF family protein
Medtr1g087920.1ERF family protein
Medtr1g090170.1ERF family protein
Medtr1g090170.2ERF family protein
Medtr1g090290.1ERF family protein
Medtr1g097190.1ERF family protein
Medtr1g098460.1ERF family protein
Medtr1g101550.1ERF family protein
Medtr1g101600.1ERF family protein
Medtr1g105400.1ERF family protein
Medtr1g110970.1ERF family protein
Medtr2g014300.1ERF family protein
Medtr2g014340.1ERF family protein
Medtr2g015040.1ERF family protein
Medtr2g015050.1ERF family protein
Medtr2g016730.1ERF family protein
Medtr2g019750.1ERF family protein
Medtr2g043020.1ERF family protein
Medtr2g043030.1ERF family protein
Medtr2g043040.1ERF family protein
Medtr2g043050.1ERF family protein
Medtr2g078680.1ERF family protein
Medtr2g085015.1ERF family protein
Medtr2g089170.1ERF family protein
Medtr2g090235.1ERF family protein
Medtr2g101340.1ERF family protein
Medtr2g103700.1ERF family protein
Medtr2g105380.1ERF family protein
Medtr2g105380.2ERF family protein
Medtr2g435590.1ERF family protein
Medtr2g438180.1ERF family protein
Medtr3g017420.1ERF family protein
Medtr3g053690.1ERF family protein
Medtr3g056750.1ERF family protein
Medtr3g057070.1ERF family protein
Medtr3g062440.1ERF family protein
Medtr3g072610.1ERF family protein
Medtr3g074130.1ERF family protein
Medtr3g090760.1ERF family protein
Medtr3g095190.1ERF family protein
Medtr3g098580.1ERF family protein
Medtr3g102100.1ERF family protein
Medtr3g102100.2ERF family protein
Medtr3g105480.1ERF family protein
Medtr3g105510.1ERF family protein
Medtr3g106290.1ERF family protein
Medtr3g107380.1ERF family protein
Medtr3g110205.1ERF family protein
Medtr3g112440.1ERF family protein
Medtr4g008860.1ERF family protein
Medtr4g009260.1ERF family protein
Medtr4g010640.1ERF family protein
Medtr4g035430.1ERF family protein
Medtr4g048250.1ERF family protein
Medtr4g054360.1ERF family protein
Medtr4g054740.1ERF family protein
Medtr4g054860.1ERF family protein
Medtr4g078710.1ERF family protein
Medtr4g082345.1ERF family protein
Medtr4g086160.1ERF family protein
Medtr4g086165.1ERF family protein
Medtr4g086190.1ERF family protein
Medtr4g086220.1ERF family protein
Medtr4g088005.1ERF family protein
Medtr4g100380.1ERF family protein
Medtr4g100420.1ERF family protein
Medtr4g100450.1ERF family protein
Medtr4g100650.1ERF family protein
Medtr4g102660.1ERF family protein
Medtr4g102670.1ERF family protein
Medtr4g111915.1ERF family protein
Medtr4g112490.1ERF family protein
Medtr4g114570.1ERF family protein
Medtr4g119270.1ERF family protein
Medtr4g134870.1ERF family protein
Medtr5g008470.1ERF family protein
Medtr5g008540.1ERF family protein
Medtr5g008550.1ERF family protein
Medtr5g008590.1ERF family protein
Medtr5g008790.1ERF family protein
Medtr5g009410.1ERF family protein
Medtr5g009620.1ERF family protein
Medtr5g010910.1ERF family protein
Medtr5g010930.1ERF family protein
Medtr5g010940.1ERF family protein
Medtr5g012910.1ERF family protein
Medtr5g016750.1ERF family protein
Medtr5g032820.1ERF family protein
Medtr5g057647.1ERF family protein
Medtr5g057810.1ERF family protein
Medtr5g058470.1ERF family protein
Medtr5g062700.1ERF family protein
Medtr5g075570.1ERF family protein
Medtr5g082950.1ERF family protein
Medtr5g083330.1ERF family protein
Medtr5g083340.1ERF family protein
Medtr5g083340.2ERF family protein
Medtr5g085070.1ERF family protein
Medtr5g085070.2ERF family protein
Medtr5g085100.1ERF family protein
Medtr5g085125.1ERF family protein
Medtr5g085130.1ERF family protein
Medtr5g095100.1ERF family protein
Medtr6g012970.1ERF family protein
Medtr6g029180.1ERF family protein
Medtr6g033255.1ERF family protein
Medtr6g037610.1ERF family protein
Medtr6g088405.1ERF family protein
Medtr6g088425.1ERF family protein
Medtr6g465420.1ERF family protein
Medtr6g465430.1ERF family protein
Medtr6g465450.1ERF family protein
Medtr6g465460.1ERF family protein
Medtr6g465510.1ERF family protein
Medtr6g465530.1ERF family protein
Medtr6g465690.1ERF family protein
Medtr6g465850.1ERF family protein
Medtr6g465990.1ERF family protein
Medtr6g466000.1ERF family protein
Medtr6g466020.1ERF family protein
Medtr6g466130.1ERF family protein
Medtr7g011630.1ERF family protein
Medtr7g020980.1ERF family protein
Medtr7g021010.1ERF family protein
Medtr7g021010.2ERF family protein
Medtr7g028925.1ERF family protein
Medtr7g046260.1ERF family protein
Medtr7g055857.1ERF family protein
Medtr7g055857.2ERF family protein
Medtr7g070220.1ERF family protein
Medtr7g081795.1ERF family protein
Medtr7g081805.1ERF family protein
Medtr7g081815.1ERF family protein
Medtr7g084370.1ERF family protein
Medtr7g085810.1ERF family protein
Medtr7g092190.1ERF family protein
Medtr7g096700.1ERF family protein
Medtr7g096750.1ERF family protein
Medtr7g096780.1ERF family protein
Medtr7g096810.1ERF family protein
Medtr7g096830.1ERF family protein
Medtr7g117690.1ERF family protein
Medtr8g006410.1ERF family protein
Medtr8g006815.1ERF family protein
Medtr8g006825.1ERF family protein
Medtr8g006840.1ERF family protein
Medtr8g010340.1ERF family protein
Medtr8g012655.1ERF family protein
Medtr8g012655.2ERF family protein
Medtr8g013860.1ERF family protein
Medtr8g022820.1ERF family protein
Medtr8g022820.2ERF family protein
Medtr8g022820.3ERF family protein
Medtr8g022820.4ERF family protein
Medtr8g023680.1ERF family protein
Medtr8g023700.1ERF family protein
Medtr8g027465.1ERF family protein
Medtr8g032610.1ERF family protein
Medtr8g069360.1ERF family protein
Medtr8g085960.1ERF family protein
Medtr8g090350.1ERF family protein
Medtr8g092460.1ERF family protein
Medtr8g099215.1ERF family protein
Medtr8g102800.1ERF family protein
ERF Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

After finding the tobacco ERFs, many proteins in the ERF family were identified and implicated in many diverse functions in cellular processes, such as hormonal signal transduction, response to biotic and abiotic stresses, regulation of metabolism, and in developmental processes in various plant species.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444


The first class are proteins which bind to ethylene response elements (ERE) or GCC boxes (tobacco EREBPs, Arabidopsis AtEBP and AtERF1-5, and tomato Pti4-6) found in the promoters of ethylene-inducible pathogenesis related genes. The GCC box is an 11 bp sequence (TAAGAGCCGCC) with a core GCCGCC sequence that is required for binding.
The second class includes proteins that bind to the C-repeat or dehydration response element (DRE) in the promoters of genes that are turned on in response to low temperatures and/or water deficit (CBF1, CBF2, CBF3/DREB1A and DREB2A). The C-repeat/DREs contain the core sequence CCGAC.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102