PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Medicago truncatula
AP2 Family
Species TF ID Description
Medtr1g017400.1AP2 family protein
Medtr2g093060.1AP2 family protein
Medtr2g093060.3AP2 family protein
Medtr2g098180.1AP2 family protein
Medtr2g460730.1AP2 family protein
Medtr3g103460.1AP2 family protein
Medtr4g007770.1AP2 family protein
Medtr4g061200.2AP2 family protein
Medtr4g061200.3AP2 family protein
Medtr4g065370.1AP2 family protein
Medtr4g094868.1AP2 family protein
Medtr4g094868.2AP2 family protein
Medtr4g094868.3AP2 family protein
Medtr4g097520.1AP2 family protein
Medtr4g127930.1AP2 family protein
Medtr4g130270.1AP2 family protein
Medtr5g015070.1AP2 family protein
Medtr5g016810.1AP2 family protein
Medtr5g016810.2AP2 family protein
Medtr5g031880.1AP2 family protein
Medtr6g011490.1AP2 family protein
Medtr7g009410.1AP2 family protein
Medtr7g080460.1AP2 family protein
Medtr7g100590.1AP2 family protein
Medtr8g020510.1AP2 family protein
Medtr8g044040.1AP2 family protein
Medtr8g044070.1AP2 family protein
Medtr8g068510.1AP2 family protein
Medtr8g468920.1AP2 family protein
Medtr2g093060.2AP2 family protein
Medtr7g091390.1AP2 family protein
Medtr4g061200.4AP2 family protein
Medtr4g061200.1AP2 family protein
Medtr1g049140.3AP2 family protein
Medtr1g049140.2AP2 family protein
Medtr1g049140.1AP2 family protein
Medtr7g061190.1AP2 family protein
AP2 Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

Genes in the AP2 family have been shown to participate in the regulation of developmental processes, e.g. flower development, spikelet meristem determinacy, leaf epidermal cell identity, and embryo development.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444


Using an in vitro selection procedure, the DNA binding specificity of the two AP2 repeat containing protein ANT was found to be 5'-gCAC(A/G)N(A/T)TcCC(a/g)ANG(c/t)-3'. This consensus site is much longer than sites recognized by proteins containing a single AP2 repeat and neither AP2 repeat of ANT was alone capable of binding to the selected sequences, suggesting that both AP2 repeats make DNA contacts.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102