PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Marchantia polymorpha
ERF Family
Species TF ID Description
Mapoly0001s0341.1.pERF family protein
Mapoly0009s0061.1.pERF family protein
Mapoly0020s0001.1.pERF family protein
Mapoly0023s0075.1.pERF family protein
Mapoly0026s0095.1.pERF family protein
Mapoly0026s0097.1.pERF family protein
Mapoly0034s0029.1.pERF family protein
Mapoly0038s0075.1.pERF family protein
Mapoly0041s0025.1.pERF family protein
Mapoly0046s0038.1.pERF family protein
Mapoly0051s0040.1.pERF family protein
Mapoly0053s0002.1.pERF family protein
Mapoly0060s0052.1.pERF family protein
Mapoly0066s0103.1.pERF family protein
Mapoly0068s0088.1.pERF family protein
Mapoly0090s0001.1.pERF family protein
Mapoly0090s0002.1.pERF family protein
Mapoly0092s0058.1.pERF family protein
Mapoly0124s0064.1.pERF family protein
Mapoly0136s0025.1.pERF family protein
Mapoly0166s0010.1.pERF family protein
Mapoly0166s0010.2.pERF family protein
Mapoly0223s0002.1.pERF family protein
Mapoly0293s0001.1.pERF family protein
ERF Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

After finding the tobacco ERFs, many proteins in the ERF family were identified and implicated in many diverse functions in cellular processes, such as hormonal signal transduction, response to biotic and abiotic stresses, regulation of metabolism, and in developmental processes in various plant species.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444


The first class are proteins which bind to ethylene response elements (ERE) or GCC boxes (tobacco EREBPs, Arabidopsis AtEBP and AtERF1-5, and tomato Pti4-6) found in the promoters of ethylene-inducible pathogenesis related genes. The GCC box is an 11 bp sequence (TAAGAGCCGCC) with a core GCCGCC sequence that is required for binding.
The second class includes proteins that bind to the C-repeat or dehydration response element (DRE) in the promoters of genes that are turned on in response to low temperatures and/or water deficit (CBF1, CBF2, CBF3/DREB1A and DREB2A). The C-repeat/DREs contain the core sequence CCGAC.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102