PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Morus notabilis
WRKY Family
Species TF ID Description
XP_010086565.1WRKY family protein
XP_010086778.1WRKY family protein
XP_010086863.1WRKY family protein
XP_010086912.1WRKY family protein
XP_010086980.1WRKY family protein
XP_010087230.1WRKY family protein
XP_010089474.1WRKY family protein
XP_010089564.1WRKY family protein
XP_010090653.1WRKY family protein
XP_010091969.1WRKY family protein
XP_010092197.1WRKY family protein
XP_010092241.1WRKY family protein
XP_010092573.1WRKY family protein
XP_010093521.1WRKY family protein
XP_010093526.1WRKY family protein
XP_010093537.1WRKY family protein
XP_010093539.1WRKY family protein
XP_010093540.1WRKY family protein
XP_010093567.1WRKY family protein
XP_010093696.1WRKY family protein
XP_010095789.1WRKY family protein
XP_010096349.1WRKY family protein
XP_010096871.1WRKY family protein
XP_010097277.1WRKY family protein
XP_010097859.1WRKY family protein
XP_010098011.1WRKY family protein
XP_010098516.1WRKY family protein
XP_010099182.1WRKY family protein
XP_010099437.1WRKY family protein
XP_010100083.1WRKY family protein
XP_010100844.1WRKY family protein
XP_010100977.1WRKY family protein
XP_010101037.1WRKY family protein
XP_010101038.1WRKY family protein
XP_010102121.1WRKY family protein
XP_010102144.1WRKY family protein
XP_010102869.1WRKY family protein
XP_010103100.1WRKY family protein
XP_010103665.1WRKY family protein
XP_010103666.1WRKY family protein
XP_010103852.1WRKY family protein
XP_010104966.1WRKY family protein
XP_010104968.1WRKY family protein
XP_010105730.1WRKY family protein
XP_010106707.1WRKY family protein
XP_010107303.1WRKY family protein
XP_010108555.1WRKY family protein
XP_010108734.1WRKY family protein
XP_010109362.1WRKY family protein
XP_010111075.1WRKY family protein
XP_010112111.1WRKY family protein
XP_010112390.1WRKY family protein
XP_010112622.1WRKY family protein
XP_010112624.1WRKY family protein
XP_010112795.1WRKY family protein
XP_010112967.1WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701