Plant Transcription Factor Database
Previous version: v1.0, v2.0, v3.0
Morus notabilis
ARF Family
Species TF ID Description
XP_010089663.1ARF family protein
XP_010089974.1ARF family protein
XP_010089977.1ARF family protein
XP_010090447.1ARF family protein
XP_010095167.1ARF family protein
XP_010099050.1ARF family protein
XP_010100039.1ARF family protein
XP_010100721.1ARF family protein
XP_010104118.1ARF family protein
XP_010104267.1ARF family protein
XP_010106165.1ARF family protein
XP_010106948.1ARF family protein
XP_010107532.1ARF family protein
XP_010111164.1ARF family protein
XP_010112723.1ARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969