PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Malus domestica
WRKY Family
Species TF ID Description
MDP0000118810WRKY family protein
MDP0000119031WRKY family protein
MDP0000119590WRKY family protein
MDP0000121669WRKY family protein
MDP0000123467WRKY family protein
MDP0000123888WRKY family protein
MDP0000125782WRKY family protein
MDP0000127976WRKY family protein
MDP0000128463WRKY family protein
MDP0000128464WRKY family protein
MDP0000129882WRKY family protein
MDP0000130400WRKY family protein
MDP0000130716WRKY family protein
MDP0000131218WRKY family protein
MDP0000133918WRKY family protein
MDP0000134105WRKY family protein
MDP0000135668WRKY family protein
MDP0000137704WRKY family protein
MDP0000142583WRKY family protein
MDP0000144203WRKY family protein
MDP0000145953WRKY family protein
MDP0000146360WRKY family protein
MDP0000146390WRKY family protein
MDP0000154734WRKY family protein
MDP0000157124WRKY family protein
MDP0000161881WRKY family protein
MDP0000168871WRKY family protein
MDP0000169621WRKY family protein
MDP0000175240WRKY family protein
MDP0000176224WRKY family protein
MDP0000177906WRKY family protein
MDP0000179145WRKY family protein
MDP0000179719WRKY family protein
MDP0000184044WRKY family protein
MDP0000184308WRKY family protein
MDP0000184361WRKY family protein
MDP0000185288WRKY family protein
MDP0000191017WRKY family protein
MDP0000193216WRKY family protein
MDP0000195385WRKY family protein
MDP0000196330WRKY family protein
MDP0000200748WRKY family protein
MDP0000201945WRKY family protein
MDP0000202292WRKY family protein
MDP0000204606WRKY family protein
MDP0000205962WRKY family protein
MDP0000215349WRKY family protein
MDP0000215371WRKY family protein
MDP0000215590WRKY family protein
MDP0000219647WRKY family protein
MDP0000228304WRKY family protein
MDP0000228328WRKY family protein
MDP0000228838WRKY family protein
MDP0000231668WRKY family protein
MDP0000231993WRKY family protein
MDP0000234335WRKY family protein
MDP0000241967WRKY family protein
MDP0000242596WRKY family protein
MDP0000247896WRKY family protein
MDP0000253189WRKY family protein
MDP0000255768WRKY family protein
MDP0000256105WRKY family protein
MDP0000256514WRKY family protein
MDP0000257129WRKY family protein
MDP0000258212WRKY family protein
MDP0000259279WRKY family protein
MDP0000260803WRKY family protein
MDP0000263349WRKY family protein
MDP0000263768WRKY family protein
MDP0000263900WRKY family protein
MDP0000263961WRKY family protein
MDP0000268364WRKY family protein
MDP0000272940WRKY family protein
MDP0000273851WRKY family protein
MDP0000275713WRKY family protein
MDP0000281965WRKY family protein
MDP0000288378WRKY family protein
MDP0000289397WRKY family protein
MDP0000290374WRKY family protein
MDP0000293456WRKY family protein
MDP0000294489WRKY family protein
MDP0000294526WRKY family protein
MDP0000294643WRKY family protein
MDP0000295812WRKY family protein
MDP0000296025WRKY family protein
MDP0000299114WRKY family protein
MDP0000299555WRKY family protein
MDP0000300712WRKY family protein
MDP0000301666WRKY family protein
MDP0000304113WRKY family protein
MDP0000307516WRKY family protein
MDP0000308261WRKY family protein
MDP0000315045WRKY family protein
MDP0000318866WRKY family protein
MDP0000319700WRKY family protein
MDP0000322257WRKY family protein
MDP0000381897WRKY family protein
MDP0000416279WRKY family protein
MDP0000418900WRKY family protein
MDP0000431358WRKY family protein
MDP0000452559WRKY family protein
MDP0000455180WRKY family protein
MDP0000460139WRKY family protein
MDP0000468391WRKY family protein
MDP0000480547WRKY family protein
MDP0000496268WRKY family protein
MDP0000505247WRKY family protein
MDP0000507805WRKY family protein
MDP0000514115WRKY family protein
MDP0000517924WRKY family protein
MDP0000566005WRKY family protein
MDP0000578301WRKY family protein
MDP0000587614WRKY family protein
MDP0000598428WRKY family protein
MDP0000602139WRKY family protein
MDP0000648338WRKY family protein
MDP0000652760WRKY family protein
MDP0000657441WRKY family protein
MDP0000676216WRKY family protein
MDP0000689162WRKY family protein
MDP0000700887WRKY family protein
MDP0000707539WRKY family protein
MDP0000708692WRKY family protein
MDP0000716551WRKY family protein
MDP0000727570WRKY family protein
MDP0000754989WRKY family protein
MDP0000756254WRKY family protein
MDP0000757476WRKY family protein
MDP0000767097WRKY family protein
MDP0000788581WRKY family protein
MDP0000792088WRKY family protein
MDP0000794439WRKY family protein
MDP0000828055WRKY family protein
MDP0000836661WRKY family protein
MDP0000849514WRKY family protein
MDP0000909869WRKY family protein
MDP0000935652WRKY family protein
MDP0000935996WRKY family protein
MDP0000946614WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701