PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Malus domestica
ERF Family
Species TF ID Description
MDP0000119204ERF family protein
MDP0000119956ERF family protein
MDP0000120147ERF family protein
MDP0000122665ERF family protein
MDP0000122739ERF family protein
MDP0000122740ERF family protein
MDP0000123172ERF family protein
MDP0000124316ERF family protein
MDP0000125673ERF family protein
MDP0000127054ERF family protein
MDP0000127123ERF family protein
MDP0000127134ERF family protein
MDP0000128326ERF family protein
MDP0000128979ERF family protein
MDP0000129941ERF family protein
MDP0000133476ERF family protein
MDP0000133485ERF family protein
MDP0000133854ERF family protein
MDP0000135205ERF family protein
MDP0000138669ERF family protein
MDP0000139446ERF family protein
MDP0000141335ERF family protein
MDP0000143745ERF family protein
MDP0000147009ERF family protein
MDP0000148178ERF family protein
MDP0000151428ERF family protein
MDP0000153436ERF family protein
MDP0000153445ERF family protein
MDP0000153866ERF family protein
MDP0000154764ERF family protein
MDP0000155057ERF family protein
MDP0000155543ERF family protein
MDP0000155743ERF family protein
MDP0000157628ERF family protein
MDP0000161249ERF family protein
MDP0000165880ERF family protein
MDP0000166779ERF family protein
MDP0000167207ERF family protein
MDP0000172065ERF family protein
MDP0000172804ERF family protein
MDP0000174352ERF family protein
MDP0000175375ERF family protein
MDP0000177547ERF family protein
MDP0000178263ERF family protein
MDP0000178398ERF family protein
MDP0000179962ERF family protein
MDP0000180950ERF family protein
MDP0000183326ERF family protein
MDP0000186131ERF family protein
MDP0000186332ERF family protein
MDP0000187369ERF family protein
MDP0000189033ERF family protein
MDP0000189347ERF family protein
MDP0000190237ERF family protein
MDP0000190504ERF family protein
MDP0000191680ERF family protein
MDP0000195376ERF family protein
MDP0000197375ERF family protein
MDP0000198054ERF family protein
MDP0000218209ERF family protein
MDP0000218344ERF family protein
MDP0000223609ERF family protein
MDP0000225376ERF family protein
MDP0000226099ERF family protein
MDP0000226115ERF family protein
MDP0000229036ERF family protein
MDP0000229285ERF family protein
MDP0000235028ERF family protein
MDP0000235313ERF family protein
MDP0000236605ERF family protein
MDP0000238848ERF family protein
MDP0000238851ERF family protein
MDP0000240840ERF family protein
MDP0000241650ERF family protein
MDP0000242611ERF family protein
MDP0000242979ERF family protein
MDP0000243113ERF family protein
MDP0000243375ERF family protein
MDP0000246184ERF family protein
MDP0000246808ERF family protein
MDP0000250924ERF family protein
MDP0000250927ERF family protein
MDP0000254227ERF family protein
MDP0000258562ERF family protein
MDP0000259085ERF family protein
MDP0000262710ERF family protein
MDP0000263008ERF family protein
MDP0000264124ERF family protein
MDP0000264187ERF family protein
MDP0000264809ERF family protein
MDP0000267651ERF family protein
MDP0000273201ERF family protein
MDP0000276536ERF family protein
MDP0000279733ERF family protein
MDP0000279943ERF family protein
MDP0000283079ERF family protein
MDP0000283350ERF family protein
MDP0000284574ERF family protein
MDP0000286915ERF family protein
MDP0000287350ERF family protein
MDP0000288465ERF family protein
MDP0000289945ERF family protein
MDP0000290585ERF family protein
MDP0000290880ERF family protein
MDP0000292965ERF family protein
MDP0000293996ERF family protein
MDP0000295902ERF family protein
MDP0000297646ERF family protein
MDP0000298677ERF family protein
MDP0000299277ERF family protein
MDP0000300382ERF family protein
MDP0000303333ERF family protein
MDP0000308379ERF family protein
MDP0000308922ERF family protein
MDP0000309801ERF family protein
MDP0000310904ERF family protein
MDP0000312701ERF family protein
MDP0000313476ERF family protein
MDP0000314191ERF family protein
MDP0000315533ERF family protein
MDP0000316694ERF family protein
MDP0000316843ERF family protein
MDP0000317932ERF family protein
MDP0000317950ERF family protein
MDP0000319194ERF family protein
MDP0000319736ERF family protein
MDP0000322279ERF family protein
MDP0000324718ERF family protein
MDP0000384932ERF family protein
MDP0000390121ERF family protein
MDP0000400129ERF family protein
MDP0000401140ERF family protein
MDP0000403580ERF family protein
MDP0000410215ERF family protein
MDP0000413387ERF family protein
MDP0000425270ERF family protein
MDP0000430682ERF family protein
MDP0000430870ERF family protein
MDP0000442215ERF family protein
MDP0000444494ERF family protein
MDP0000445110ERF family protein
MDP0000446783ERF family protein
MDP0000447570ERF family protein
MDP0000451365ERF family protein
MDP0000453797ERF family protein
MDP0000457509ERF family protein
MDP0000464704ERF family protein
MDP0000466331ERF family protein
MDP0000467753ERF family protein
MDP0000478356ERF family protein
MDP0000513140ERF family protein
MDP0000517257ERF family protein
MDP0000517262ERF family protein
MDP0000525933ERF family protein
MDP0000528870ERF family protein
MDP0000537425ERF family protein
MDP0000542633ERF family protein
MDP0000551969ERF family protein
MDP0000566690ERF family protein
MDP0000567264ERF family protein
MDP0000612884ERF family protein
MDP0000628484ERF family protein
MDP0000629527ERF family protein
MDP0000633218ERF family protein
MDP0000634630ERF family protein
MDP0000649022ERF family protein
MDP0000652413ERF family protein
MDP0000654314ERF family protein
MDP0000665685ERF family protein
MDP0000668122ERF family protein
MDP0000675982ERF family protein
MDP0000679280ERF family protein
MDP0000683814ERF family protein
MDP0000689946ERF family protein
MDP0000692632ERF family protein
MDP0000703626ERF family protein
MDP0000704216ERF family protein
MDP0000743350ERF family protein
MDP0000744693ERF family protein
MDP0000755622ERF family protein
MDP0000756341ERF family protein
MDP0000759299ERF family protein
MDP0000764803ERF family protein
MDP0000778140ERF family protein
MDP0000783818ERF family protein
MDP0000787281ERF family protein
MDP0000789227ERF family protein
MDP0000790788ERF family protein
MDP0000791464ERF family protein
MDP0000805422ERF family protein
MDP0000825712ERF family protein
MDP0000827400ERF family protein
MDP0000829925ERF family protein
MDP0000830129ERF family protein
MDP0000833641ERF family protein
MDP0000839828ERF family protein
MDP0000842644ERF family protein
MDP0000848905ERF family protein
MDP0000854039ERF family protein
MDP0000855671ERF family protein
MDP0000861708ERF family protein
MDP0000865032ERF family protein
MDP0000868587ERF family protein
MDP0000871361ERF family protein
MDP0000871689ERF family protein
MDP0000873258ERF family protein
MDP0000876858ERF family protein
MDP0000880063ERF family protein
MDP0000880312ERF family protein
MDP0000890854ERF family protein
MDP0000894895ERF family protein
MDP0000907929ERF family protein
MDP0000923579ERF family protein
MDP0000923690ERF family protein
MDP0000930655ERF family protein
MDP0000932292ERF family protein
ERF Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

After finding the tobacco ERFs, many proteins in the ERF family were identified and implicated in many diverse functions in cellular processes, such as hormonal signal transduction, response to biotic and abiotic stresses, regulation of metabolism, and in developmental processes in various plant species.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444


The first class are proteins which bind to ethylene response elements (ERE) or GCC boxes (tobacco EREBPs, Arabidopsis AtEBP and AtERF1-5, and tomato Pti4-6) found in the promoters of ethylene-inducible pathogenesis related genes. The GCC box is an 11 bp sequence (TAAGAGCCGCC) with a core GCCGCC sequence that is required for binding.
The second class includes proteins that bind to the C-repeat or dehydration response element (DRE) in the promoters of genes that are turned on in response to low temperatures and/or water deficit (CBF1, CBF2, CBF3/DREB1A and DREB2A). The C-repeat/DREs contain the core sequence CCGAC.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102