PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Linum usitatissimum
AP2 Family
Species TF ID Description
Lus10001553AP2 family protein
Lus10002657AP2 family protein
Lus10004990AP2 family protein
Lus10005253AP2 family protein
Lus10007719AP2 family protein
Lus10008939AP2 family protein
Lus10009374AP2 family protein
Lus10012728AP2 family protein
Lus10013268AP2 family protein
Lus10015055AP2 family protein
Lus10018124AP2 family protein
Lus10018655AP2 family protein
Lus10019331AP2 family protein
Lus10019905AP2 family protein
Lus10023165AP2 family protein
Lus10024101AP2 family protein
Lus10026477AP2 family protein
Lus10028880AP2 family protein
Lus10030671AP2 family protein
Lus10030792AP2 family protein
Lus10031260AP2 family protein
Lus10031831AP2 family protein
Lus10036141AP2 family protein
Lus10036719AP2 family protein
Lus10037209AP2 family protein
Lus10037670AP2 family protein
Lus10041595AP2 family protein
Lus10041618AP2 family protein
Lus10005513AP2 family protein
Lus10011730AP2 family protein
Lus10039650AP2 family protein
Lus10000965AP2 family protein
Lus10040140AP2 family protein
Lus10001979AP2 family protein
Lus10040365AP2 family protein
AP2 Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

Genes in the AP2 family have been shown to participate in the regulation of developmental processes, e.g. flower development, spikelet meristem determinacy, leaf epidermal cell identity, and embryo development.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444

Using an in vitro selection procedure, the DNA binding specificity of the two AP2 repeat containing protein ANT was found to be 5'-gCAC(A/G)N(A/T)TcCC(a/g)ANG(c/t)-3'. This consensus site is much longer than sites recognized by proteins containing a single AP2 repeat and neither AP2 repeat of ANT was alone capable of binding to the selected sequences, suggesting that both AP2 repeats make DNA contacts.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102