PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Lactuca sativa
bZIP Family
Species TF ID Description
Lsa000919bZIP family protein
Lsa001051bZIP family protein
Lsa001275bZIP family protein
Lsa001326bZIP family protein
Lsa001515bZIP family protein
Lsa001806bZIP family protein
Lsa002079bZIP family protein
Lsa002096bZIP family protein
Lsa002273bZIP family protein
Lsa002494bZIP family protein
Lsa002628bZIP family protein
Lsa003310bZIP family protein
Lsa003509bZIP family protein
Lsa003521bZIP family protein
Lsa003778bZIP family protein
Lsa003827bZIP family protein
Lsa004020bZIP family protein
Lsa004053bZIP family protein
Lsa005596bZIP family protein
Lsa005737bZIP family protein
Lsa006218bZIP family protein
Lsa006591bZIP family protein
Lsa006722bZIP family protein
Lsa007038bZIP family protein
Lsa007138bZIP family protein
Lsa007447bZIP family protein
Lsa007598bZIP family protein
Lsa007712bZIP family protein
Lsa008041bZIP family protein
Lsa009386bZIP family protein
Lsa009713bZIP family protein
Lsa010229bZIP family protein
Lsa010406bZIP family protein
Lsa010595bZIP family protein
Lsa012166bZIP family protein
Lsa012515bZIP family protein
Lsa013780bZIP family protein
Lsa013995bZIP family protein
Lsa015152bZIP family protein
Lsa015158bZIP family protein
Lsa015941bZIP family protein
Lsa016592bZIP family protein
Lsa016620bZIP family protein
Lsa016968bZIP family protein
Lsa017090bZIP family protein
Lsa017208bZIP family protein
Lsa017385bZIP family protein
Lsa017868bZIP family protein
Lsa018740bZIP family protein
Lsa019204bZIP family protein
Lsa019207bZIP family protein
Lsa002178bZIP family protein
Lsa004808bZIP family protein
Lsa006394bZIP family protein
Lsa015215bZIP family protein
Lsa015431bZIP family protein
Lsa017255bZIP family protein
Lsa017742bZIP family protein
bZIP Family Introduction

The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.

Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Jakoby M, Weisshaar B, Droge-Laser W, Vicente-Carbajosa J, Tiedemann J, Kroj T, Parcy F
bZIP transcription factors in Arabidopsis.
Trends Plant Sci, 2002. 7(3): p. 106-11.
PMID: 11906833