PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Lactuca sativa
TALE Family
Species TF ID Description
Lsa000647TALE family protein
Lsa003749TALE family protein
Lsa016310TALE family protein
Lsa016601TALE family protein
Lsa016337TALE family protein
Lsa002854TALE family protein
Lsa015859TALE family protein
Lsa012157TALE family protein
Lsa012404TALE family protein
Lsa013315TALE family protein
Lsa001015TALE family protein
Lsa008440TALE family protein
Lsa008517TALE family protein
Lsa011992TALE family protein
Lsa010100TALE family protein
Lsa010781TALE family protein
TALE Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401


the three-amino-acid-loop-extension (TALE) class of homeoproteins has been shown to control meristem formation and/or maintenance, organ morphogenesis, organ position, and several aspects of the reproductive phase. This family contains the KNOTTED-like homeodomain (KNOX) and BEL1-like Homeodomain (BELL) members, which function as heterodimers.

Hamant O, Pautot V.
Plant development: a TALE story.
C R Biol, 2010. 333(4): p. 371-81.
PMID: 20371112