PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Lactuca sativa
NAC Family
Species TF ID Description
Lsa000602NAC family protein
Lsa000820NAC family protein
Lsa001397NAC family protein
Lsa001658NAC family protein
Lsa002776NAC family protein
Lsa002920NAC family protein
Lsa003012NAC family protein
Lsa003093NAC family protein
Lsa003627NAC family protein
Lsa003641NAC family protein
Lsa004975NAC family protein
Lsa005206NAC family protein
Lsa005319NAC family protein
Lsa005632NAC family protein
Lsa006253NAC family protein
Lsa006424NAC family protein
Lsa006465NAC family protein
Lsa006615NAC family protein
Lsa006959NAC family protein
Lsa007052NAC family protein
Lsa007562NAC family protein
Lsa007753NAC family protein
Lsa008217NAC family protein
Lsa008320NAC family protein
Lsa008324NAC family protein
Lsa008924NAC family protein
Lsa009990NAC family protein
Lsa010115NAC family protein
Lsa011065NAC family protein
Lsa011669NAC family protein
Lsa014287NAC family protein
Lsa014343NAC family protein
Lsa014378NAC family protein
Lsa014428NAC family protein
Lsa014722NAC family protein
Lsa014934NAC family protein
Lsa015455NAC family protein
Lsa015516NAC family protein
Lsa015559NAC family protein
Lsa016181NAC family protein
Lsa016324NAC family protein
Lsa016895NAC family protein
Lsa017437NAC family protein
Lsa017607NAC family protein
Lsa018128NAC family protein
Lsa018582NAC family protein
Lsa019421NAC family protein
Lsa003913NAC family protein
Lsa005481NAC family protein
Lsa007133NAC family protein
Lsa007688NAC family protein
Lsa010199NAC family protein
Lsa011674NAC family protein
Lsa017657NAC family protein
NAC Family Introduction

NAM, ATAF, and CUC (NAC) transcription factors comprise a large protein family. Proteins of this family contain a highly conserved N-terminal DNA-binding domain and a variable C-terminal domain (Xie et al. 2000; Duval et al. 2002; Ernst et al. 2004; Olsen et al. 2005). NAC was originally derived from the names of three proteins, no apical meristem (NAM), ATAF1-2, and CUC2 (cup-shaped cotyledon), that contain a similar DNA-binding domain (Souer et al. 1996; Aida et al. 1997). The early reported NAC transcription factors are implicated in various aspects of plant development. A few examples are NAM from Petunia (Souer et al. 1996) and CUC1-2 (Aida et al. 1997) from Arabidopsis which have roles in controlling the formation of boundary cells of the meristem; NAP (Sablowski and Meyerowitz 1998) from Arabidopsis which acts as a target gene of AP3/PI and functions in the transition between cell division and cell expansion in stamens and petals; and AtNAC1 which mediates auxin signaling to promote lateral root development (Xie et al. 2000). Recently, a few NAC transcription factors were reported to play an essential role in regulating senescence, cell division, and wood formation (Ishida et al. 2000; Takada et al. 2001; Vroemen et al. 2003; Weir et al. 2004; Kubo et al. 2005; Kim et al. 2006; Zhong et al. 2006; Demura and Fukuda 2007; Ko et al. 2007; Mitsuda et al. 2007; Zhong et al. 2007).

NAM, ATAF, and CUC proteins were also found to participate in plant responses to pathogens, viral infections, and environmental stimuli (Xie et al. 1999; Ren et al. 2000; Collinge and Boller 2001; Kim et al. 2007). In Arabidopsis, three NAC genes, ANAC019, ANAC055, and ANAC072, were induced by drought, salinity, and/or low temperature (Tran et al. 2004), and the transgenic Arabidopsis plants overexpressing these genes showed improved stress tolerance compared to the wild type (Tran et al. 2004). Furthermore, proteins of these genes can bind to a ciselement containing CATGTG motif (Tran et al. 2004).

Fang Y, You J, Xie K, Xie W, Xiong L.
Systematic sequence analysis and identification of tissue-specific or stress-responsive genes of NAC transcription factor family in rice.
Mol Genet Genomics, 2008. 280(6): p. 547-63.
PMID: 18813954