PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Lactuca sativa
LBD Family
Species TF ID Description
Lsa000537LBD family protein
Lsa001931LBD family protein
Lsa002914LBD family protein
Lsa006993LBD family protein
Lsa008990LBD family protein
Lsa010736LBD family protein
Lsa011362LBD family protein
Lsa012107LBD family protein
Lsa013034LBD family protein
Lsa013334LBD family protein
Lsa017218LBD family protein
Lsa017702LBD family protein
Lsa017857LBD family protein
Lsa019225LBD family protein
LBD Family Introduction

The in vitro DNA-binding and heterologous transcriptional activation studies presented here indicate that the LBD protein family represents a new class of DNA-binding transcription factors that recognize the cis-element GCGGCG. The DNA-binding activity is present within the LOB domain, which is conserved throughout the 43 Arabidopsis family members as well as LBD proteins in other plant species.

the LBD genes encode a novel class of DNA-binding transcription factors. Post-translational regulation of transcription factors is often crucial for control of gene expression. In our study, we demonstrate that members of the basic helix-loop-helix (bHLH) family of transcription factors are capable of interacting with LOB. The expression patterns of bHLH048 and LOB overlap at lateral organ boundaries. Interestingly, the interaction of bHLH048 with LOB results in reduced affinity of LOB for the consensus DNA motif. Thus, our studies suggest that bHLH048 post-translationally regulates the function of LOB at lateral organ boundaries.

Aman Husbands, Elizabeth M. Bell, Bin Shuai, Harley M.S. Smith, and Patricia S. Springer.
LATERAL ORGAN BOUNDARIES defines a new family of DNA-binding transcription factors and can interact with specific bHLH proteins.
Nucleic Acids Res, 2007. 35(19): p. 6663-71.
PMID: 17913740