PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Lactuca sativa
G2-like Family
Species TF ID Description
Lsa001109G2-like family protein
Lsa002539G2-like family protein
Lsa003855G2-like family protein
Lsa005111G2-like family protein
Lsa005369G2-like family protein
Lsa006043G2-like family protein
Lsa006566G2-like family protein
Lsa006915G2-like family protein
Lsa007417G2-like family protein
Lsa008155G2-like family protein
Lsa008712G2-like family protein
Lsa009420G2-like family protein
Lsa010629G2-like family protein
Lsa012539G2-like family protein
Lsa013206G2-like family protein
Lsa014027G2-like family protein
Lsa015105G2-like family protein
Lsa015216G2-like family protein
Lsa015313G2-like family protein
Lsa015620G2-like family protein
Lsa018542G2-like family protein
Lsa018546G2-like family protein
Lsa019160G2-like family protein
Lsa002401G2-like family protein
Lsa010345G2-like family protein
Lsa012846G2-like family protein
Lsa015228G2-like family protein
Lsa017734G2-like family protein
Lsa017783G2-like family protein
G2-like Family Introduction

The GLK proteins are members of the recently categorized GARP superfamily of transcription factors (Riechmann et al., 2000) defined by G2 in maize; the Arabidopsis RESPONSE REGULATOR-B (ARR-B) proteins (Imamura et al., 1999); and the PHOSPHATE STARVATION RESPONSE1 (PSR1) protein of Chlamydomonas (Wykoff et al., 1999). In the case of G2, three of the four defining features of most transcription factors have been verified experimentally in heterologous systems. G2 is nuclearlocalized (Hall et al., 1998), is able to transactivate reporter gene expression, and can both homo-dimerize and heterodimerize with ZmGLK1 (Rossini et al., 2001). DNA-binding activity of GLK proteins has yet to be demonstrated,however, the putative DNA-binding domain is highly conserved with domains in other GARP proteins such as ARR1 and ARR2 (Riechmann et al., 2000). Notably, ARR1 and ARR2 have been shown to bind DNA (Sakai et al.,2000), thus it is likely that GLK proteins act as transcriptional regulators of chloroplast development.

The GLK proteins are members of the GARP superfamily of transcription factors, and phylogenetic analysis demonstrates that the maize, rice and Arabidopsis GLK gene pairs comprise a distinct group within the GARP superfamily. Further phylogenetic analysis suggests that the gene pairs arose through separate duplication events in the monocot and dicot lineages. As in rice, AtGLK1 and AtGLK2 are expressed in partially overlapping domains in photosynthetic tissue. GLK genes therefore regulate chloroplast development in diverse plant species.

Fitter DW, Martin DJ, Copley MJ, Scotland RW, Langdale JA.
GLK gene pairs regulate chloroplast development in diverse plant species.
Plant J. 2002 Sep;31(6):713-27.
PMID: 12220263