PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Leersia perrieri
bHLH Family
Species TF ID Description
LPERR01G00310.1bHLH family protein
LPERR01G00520.1bHLH family protein
LPERR01G00530.1bHLH family protein
LPERR01G00690.1bHLH family protein
LPERR01G03590.1bHLH family protein
LPERR01G05820.1bHLH family protein
LPERR01G07000.1bHLH family protein
LPERR01G07720.1bHLH family protein
LPERR01G10950.1bHLH family protein
LPERR01G10950.2bHLH family protein
LPERR01G11210.1bHLH family protein
LPERR01G11210.2bHLH family protein
LPERR01G14580.1bHLH family protein
LPERR01G15620.1bHLH family protein
LPERR01G17090.1bHLH family protein
LPERR01G17450.1bHLH family protein
LPERR01G24170.1bHLH family protein
LPERR01G24260.1bHLH family protein
LPERR01G28210.1bHLH family protein
LPERR01G28210.2bHLH family protein
LPERR01G28830.1bHLH family protein
LPERR01G31030.1bHLH family protein
LPERR01G32940.1bHLH family protein
LPERR01G32940.2bHLH family protein
LPERR01G32940.3bHLH family protein
LPERR01G32940.4bHLH family protein
LPERR01G35240.1bHLH family protein
LPERR01G36170.1bHLH family protein
LPERR01G36170.2bHLH family protein
LPERR01G37160.1bHLH family protein
LPERR01G38470.1bHLH family protein
LPERR02G01020.1bHLH family protein
LPERR02G01320.1bHLH family protein
LPERR02G01320.2bHLH family protein
LPERR02G07820.1bHLH family protein
LPERR02G08270.1bHLH family protein
LPERR02G09400.1bHLH family protein
LPERR02G12290.1bHLH family protein
LPERR02G12290.2bHLH family protein
LPERR02G15950.1bHLH family protein
LPERR02G17000.1bHLH family protein
LPERR02G18900.1bHLH family protein
LPERR02G23260.1bHLH family protein
LPERR02G23970.1bHLH family protein
LPERR02G24230.1bHLH family protein
LPERR02G25270.1bHLH family protein
LPERR02G25270.2bHLH family protein
LPERR02G25270.3bHLH family protein
LPERR02G26590.1bHLH family protein
LPERR02G27220.1bHLH family protein
LPERR02G29460.1bHLH family protein
LPERR02G30060.1bHLH family protein
LPERR03G01610.1bHLH family protein
LPERR03G02580.1bHLH family protein
LPERR03G04690.4bHLH family protein
LPERR03G04710.1bHLH family protein
LPERR03G05820.1bHLH family protein
LPERR03G08340.1bHLH family protein
LPERR03G08460.1bHLH family protein
LPERR03G08460.2bHLH family protein
LPERR03G10060.1bHLH family protein
LPERR03G11180.1bHLH family protein
LPERR03G16670.1bHLH family protein
LPERR03G16670.2bHLH family protein
LPERR03G21650.1bHLH family protein
LPERR03G22350.1bHLH family protein
LPERR03G22450.1bHLH family protein
LPERR03G22450.2bHLH family protein
LPERR03G22450.3bHLH family protein
LPERR03G22450.4bHLH family protein
LPERR03G22450.5bHLH family protein
LPERR03G22450.6bHLH family protein
LPERR03G24050.1bHLH family protein
LPERR03G27220.1bHLH family protein
LPERR03G27440.1bHLH family protein
LPERR03G28140.1bHLH family protein
LPERR03G29370.1bHLH family protein
LPERR03G29370.2bHLH family protein
LPERR03G29580.1bHLH family protein
LPERR03G30650.1bHLH family protein
LPERR03G30650.2bHLH family protein
LPERR03G31640.1bHLH family protein
LPERR03G32000.1bHLH family protein
LPERR03G32730.1bHLH family protein
LPERR04G04510.1bHLH family protein
LPERR04G04510.2bHLH family protein
LPERR04G04510.3bHLH family protein
LPERR04G04520.1bHLH family protein
LPERR04G05850.1bHLH family protein
LPERR04G07210.1bHLH family protein
LPERR04G09510.1bHLH family protein
LPERR04G09530.1bHLH family protein
LPERR04G09540.1bHLH family protein
LPERR04G09550.1bHLH family protein
LPERR04G13560.4bHLH family protein
LPERR04G17380.1bHLH family protein
LPERR04G17380.2bHLH family protein
LPERR04G17380.3bHLH family protein
LPERR04G17390.1bHLH family protein
LPERR04G17390.2bHLH family protein
LPERR04G17390.3bHLH family protein
LPERR04G17400.1bHLH family protein
LPERR04G17400.2bHLH family protein
LPERR04G19210.1bHLH family protein
LPERR04G19640.1bHLH family protein
LPERR04G22000.1bHLH family protein
LPERR04G22650.1bHLH family protein
LPERR05G00200.1bHLH family protein
LPERR05G02370.1bHLH family protein
LPERR05G03680.1bHLH family protein
LPERR05G03980.1bHLH family protein
LPERR05G05410.1bHLH family protein
LPERR05G17760.1bHLH family protein
LPERR05G20190.1bHLH family protein
LPERR05G23220.1bHLH family protein
LPERR05G23890.1bHLH family protein
LPERR06G03910.1bHLH family protein
LPERR06G03910.2bHLH family protein
LPERR06G04980.1bHLH family protein
LPERR06G05570.1bHLH family protein
LPERR06G05570.2bHLH family protein
LPERR06G05570.3bHLH family protein
LPERR06G05570.4bHLH family protein
LPERR06G05570.5bHLH family protein
LPERR06G06410.1bHLH family protein
LPERR06G07460.1bHLH family protein
LPERR06G09390.1bHLH family protein
LPERR06G13950.1bHLH family protein
LPERR06G15630.1bHLH family protein
LPERR06G17540.1bHLH family protein
LPERR06G23280.1bHLH family protein
LPERR07G02450.1bHLH family protein
LPERR07G04600.1bHLH family protein
LPERR07G05350.1bHLH family protein
LPERR07G06180.1bHLH family protein
LPERR07G15060.1bHLH family protein
LPERR07G15500.1bHLH family protein
LPERR07G17840.1bHLH family protein
LPERR07G20030.1bHLH family protein
LPERR08G01030.1bHLH family protein
LPERR08G02470.1bHLH family protein
LPERR08G04630.1bHLH family protein
LPERR08G11070.1bHLH family protein
LPERR08G11070.2bHLH family protein
LPERR08G11070.3bHLH family protein
LPERR08G12910.1bHLH family protein
LPERR08G14680.1bHLH family protein
LPERR08G15030.1bHLH family protein
LPERR08G15350.1bHLH family protein
LPERR08G15600.1bHLH family protein
LPERR08G15680.1bHLH family protein
LPERR08G15680.2bHLH family protein
LPERR08G16800.1bHLH family protein
LPERR08G17860.1bHLH family protein
LPERR08G18570.1bHLH family protein
LPERR08G19100.1bHLH family protein
LPERR09G06880.1bHLH family protein
LPERR09G07210.1bHLH family protein
LPERR09G09120.1bHLH family protein
LPERR09G09700.1bHLH family protein
LPERR09G10040.1bHLH family protein
LPERR09G10040.2bHLH family protein
LPERR09G10080.1bHLH family protein
LPERR09G10080.2bHLH family protein
LPERR09G10080.3bHLH family protein
LPERR09G10080.4bHLH family protein
LPERR09G10080.5bHLH family protein
LPERR09G10800.1bHLH family protein
LPERR09G11560.1bHLH family protein
LPERR09G12170.1bHLH family protein
LPERR09G12780.1bHLH family protein
LPERR10G05620.1bHLH family protein
LPERR10G06610.1bHLH family protein
LPERR10G06640.1bHLH family protein
LPERR10G14070.1bHLH family protein
LPERR10G14070.2bHLH family protein
LPERR10G14070.3bHLH family protein
LPERR10G15300.1bHLH family protein
LPERR11G03270.1bHLH family protein
LPERR11G09930.1bHLH family protein
LPERR11G11940.1bHLH family protein
LPERR11G15400.1bHLH family protein
LPERR11G15450.1bHLH family protein
LPERR11G16970.1bHLH family protein
LPERR12G10620.1bHLH family protein
LPERR12G11190.1bHLH family protein
LPERR12G11960.1bHLH family protein
LPERR12G14550.1bHLH family protein
LPERR12G14980.1bHLH family protein
LPERR12G14990.1bHLH family protein
LPERR12G15000.1bHLH family protein
LPERR12G15010.1bHLH family protein
LPERR12G15470.1bHLH family protein
LPERR12G16560.1bHLH family protein
bHLH Family Introduction

The basic/helix-loop-helix (bHLH) proteins are a superfamily of transcription factors that have been well characterized in nonplant eukaryotes, especially in mammalian systems, in which considerable structural, functional, and phylogenetic analyses have been performed. The data indicate that bHLH proteins are important regulatory components in transcriptional networks in these systems, controlling a diversity of processes from cell proliferation to cell lineage establishment.

This family is defined by the bHLH signature domain, which consists of 60 amino acids with two functionally distinct regions. The basic region, located at the N-terminal end of the domain, is involved in DNA binding and consists of 15 amino acids with a high number of basic residues. The HLH region, at the C-terminal end, functions as a dimerization domain and is constituted mainly of hydrophobic residues that form two amphipathic -helices separated by a loop region of variable sequence and length. Outside of the conserved bHLH domain, these proteins exhibit considerable sequence divergence. Cocrystal structural analysis has shown that the interaction between the HLH regions of two separate polypeptides leads to the formation of homodimers and/or heterodimers and that the basic region of each partner binds to half of the DNA recognition sequence. Some bHLH proteins form homodimers or restrict their heterodimerization activity to closely related members of the family. On the other hand, some can form heterodimers with one or several different partners.

The core DNA sequence motif recognized by the bHLH proteins is a consensus hexanucleotide sequence known as the E-box (5'-CANNTG-3'). There are different types of E-boxes, depending on the identity of the two central bases. One of the most common is the palindromic G-box (5'-CACGTG-3'). Certain conserved amino acids within the basic region of the protein provide recognition of the core consensus site, whereas other residues in the domain dictate specificity for a given type of E-box . In addition, flanking nucleotides outside of the hexanucleotide core have been shown to play a role in binding specificity, and there is evidence that a loop residue in the protein plays a role in DNA binding through elements that lie outside of the core recognition sequence.

Toledo-Ortiz G, Huq E, Quail PH.
The Arabidopsis basic/helix-loop-helix transcription factor family.
Plant Cell. 2003 Aug;15(8):1749-70
PMID: 12897250