PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Kalanchoe laxiflora
FAR1 Family
Species TF ID Description
Kaladp0007s0082.1.pFAR1 family protein
Kaladp0007s0085.1.pFAR1 family protein
Kaladp0008s0388.1.pFAR1 family protein
Kaladp0008s0392.1.pFAR1 family protein
Kaladp0011s0042.1.pFAR1 family protein
Kaladp0011s0074.1.pFAR1 family protein
Kaladp0011s1252.1.pFAR1 family protein
Kaladp0015s0089.1.pFAR1 family protein
Kaladp0018s0192.1.pFAR1 family protein
Kaladp0020s0040.1.pFAR1 family protein
Kaladp0020s0040.2.pFAR1 family protein
Kaladp0020s0040.3.pFAR1 family protein
Kaladp0020s0040.4.pFAR1 family protein
Kaladp0020s0040.5.pFAR1 family protein
Kaladp0020s0154.1.pFAR1 family protein
Kaladp0024s0414.1.pFAR1 family protein
Kaladp0027s0036.1.pFAR1 family protein
Kaladp0027s0036.2.pFAR1 family protein
Kaladp0032s0111.1.pFAR1 family protein
Kaladp0032s0456.1.pFAR1 family protein
Kaladp0033s0338.1.pFAR1 family protein
Kaladp0035s0029.1.pFAR1 family protein
Kaladp0035s0029.2.pFAR1 family protein
Kaladp0035s0029.3.pFAR1 family protein
Kaladp0035s0029.4.pFAR1 family protein
Kaladp0035s0029.5.pFAR1 family protein
Kaladp0044s0003.1.pFAR1 family protein
Kaladp0045s0237.10.pFAR1 family protein
Kaladp0045s0237.11.pFAR1 family protein
Kaladp0045s0237.1.pFAR1 family protein
Kaladp0045s0237.2.pFAR1 family protein
Kaladp0045s0237.3.pFAR1 family protein
Kaladp0045s0237.4.pFAR1 family protein
Kaladp0045s0237.5.pFAR1 family protein
Kaladp0045s0237.6.pFAR1 family protein
Kaladp0045s0237.7.pFAR1 family protein
Kaladp0045s0237.8.pFAR1 family protein
Kaladp0045s0237.9.pFAR1 family protein
Kaladp0045s0309.1.pFAR1 family protein
Kaladp0045s0309.2.pFAR1 family protein
Kaladp0045s0309.3.pFAR1 family protein
Kaladp0046s0096.1.pFAR1 family protein
Kaladp0046s0097.1.pFAR1 family protein
Kaladp0046s0097.2.pFAR1 family protein
Kaladp0048s0935.1.pFAR1 family protein
Kaladp0055s0290.1.pFAR1 family protein
Kaladp0058s0028.1.pFAR1 family protein
Kaladp0058s0550.1.pFAR1 family protein
Kaladp0058s0550.2.pFAR1 family protein
Kaladp0059s0147.1.pFAR1 family protein
Kaladp0059s0161.1.pFAR1 family protein
Kaladp0060s0330.1.pFAR1 family protein
Kaladp0061s0003.1.pFAR1 family protein
Kaladp0061s0138.1.pFAR1 family protein
Kaladp0068s0291.1.pFAR1 family protein
Kaladp0069s0062.1.pFAR1 family protein
Kaladp0076s0225.1.pFAR1 family protein
Kaladp0083s0081.1.pFAR1 family protein
Kaladp0085s0150.1.pFAR1 family protein
Kaladp0088s0008.1.pFAR1 family protein
Kaladp0091s0087.1.pFAR1 family protein
Kaladp0092s0144.1.pFAR1 family protein
Kaladp0131s0001.1.pFAR1 family protein
Kaladp0167s0008.1.pFAR1 family protein
Kaladp0167s0008.2.pFAR1 family protein
Kaladp0399s0002.1.pFAR1 family protein
Kaladp0430s0001.1.pFAR1 family protein
Kaladp0488s0024.1.pFAR1 family protein
Kaladp0488s0024.2.pFAR1 family protein
Kaladp0488s0024.3.pFAR1 family protein
Kaladp0488s0024.4.pFAR1 family protein
Kaladp0488s0024.5.pFAR1 family protein
Kaladp0488s0024.6.pFAR1 family protein
Kaladp0488s0024.7.pFAR1 family protein
Kaladp0488s0024.8.pFAR1 family protein
Kaladp0515s0031.1.pFAR1 family protein
Kaladp0515s0031.2.pFAR1 family protein
Kaladp0515s0031.4.pFAR1 family protein
Kaladp0515s0031.5.pFAR1 family protein
Kaladp0515s0212.1.pFAR1 family protein
Kaladp0515s0212.2.pFAR1 family protein
Kaladp0589s0005.1.pFAR1 family protein
FAR1 Family Introduction

We show that Arabidopsis FHY3 and FAR1, which encode two proteins related to Mutator-like transposases, act together to modulate phyA signaling by directly activating the transcription of FHY1 and FHL, whose products are essential for light-induced phyA nuclear accumulation and subsequent light responses. FHY3 and FAR1 have separable DNA binding and transcriptional activation domains that are highly conserved in Mutator-like transposases. Further, expression of FHY3 and FAR1 is negatively regulated by phyA signaling. We propose that FHY3 and FAR1 represent transcription factors that have been co-opted from an ancient Mutator-like transposase(s) to modulate phyA-signaling homeostasis in higher plants.

We next used a yeast one-hybrid assay to delineate the DNA sequences to which FHY3 and FAR1 bind. GAD-FHY3 or GAD-FAR1 fusion proteins (GAD, GAL4 transcriptional activation domain), but not GAD alone, activated the LacZ reporter genes driven by the FHY1 and FHL promoters. Deletion analysis narrowed down the FHY3/FAR1 binding site to a 39-bp promoter subfragment located on the "a" fragment for both FHY1 and FHL. Notably, these subfragments share a stretch of consensus sequence, 5'-TTCACGCGCC-3'. Mutating the core sequence "CACGCGC" of this motif (m2 and m3 for FHY1, m5 for FHL) abolished the reporter gene activation by both GAD-FHY3 and GAD-FAR1. Mutating the flanking sequences (m1 and m4) did not obviously affect the reporter gene activation by GAD-FAR1, but clearly reduced activation by GAD-FHY3. Thus, "CACGCGC" likely defines a cis-element that confers specific binding for FHY3 and FAR1 and is named FBS for FHY3-FAR1 binding site.

Lin R, Ding L, Casola C, Ripoll DR, Feschotte C, Wang H.
Transposase-derived transcription factors regulate light signaling in Arabidopsis.
Science, 2007. 318(5854): p. 1302-5.
PMID: 18033885