PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Kalanchoe laxiflora
BES1 Family
Species TF ID Description
Kaladp0008s0122.1.pBES1 family protein
Kaladp0011s0808.1.pBES1 family protein
Kaladp0011s1364.1.pBES1 family protein
Kaladp0019s0060.1.pBES1 family protein
Kaladp0021s0098.1.pBES1 family protein
Kaladp0024s0413.1.pBES1 family protein
Kaladp0024s0896.1.pBES1 family protein
Kaladp0053s0089.1.pBES1 family protein
Kaladp0060s0104.1.pBES1 family protein
Kaladp0081s0015.1.pBES1 family protein
Kaladp0099s0016.1.pBES1 family protein
Kaladp0172s0023.1.pBES1 family protein
Kaladp0172s0023.2.pBES1 family protein
Kaladp0172s0023.3.pBES1 family protein
Kaladp0172s0023.4.pBES1 family protein
Kaladp0172s0023.5.pBES1 family protein
Kaladp0630s0039.1.pBES1 family protein
BES1 Family Introduction

Brassinosteroids (BRs) signal through a plasma membrane-localized receptor kinase to regulate plant growth and development. We showed previously that a novel protein, BES1(BRI1-EMS-SUPPRESSOR 1), accumulates in the nucleus in response to BRs, where it plays a role in BR-regulated gene expression; however, the mechanism by which BES1 regulates gene expression is unknown. In this study, we dissect BES1 subdomains and establish that BES1 is a transcription factor that binds to and activates BR target gene promoters both in vitro and in vivo. BES1 interacts with a basic helix-loop-helix protein, BIM1, to synergistically bind to E box (CANNTG) sequences present in many BR-induced promoters. Loss-of-function and gain-of-function mutants of BIM1 and its close family members display BR response phenotypes. Thus, BES1 defines a new class of plant-specific transcription factors that cooperate with transcription factors such as BIM1 to regulate BR-induced genes.

Yin Y, Vafeados D, Tao Y, Yoshida S, Asami T, Chory J.
A new class of transcription factors mediates brassinosteroid-regulated gene expression in Arabidopsis.
Cell. 2005 Jan 28;120(2):249-59.
PMID: 15680330