PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Juglans regia
ARF Family
Species TF ID Description
WALNUT_00004830-RAARF family protein
WALNUT_00006775-RAARF family protein
WALNUT_00007047-RAARF family protein
WALNUT_00008048-RAARF family protein
WALNUT_00008122-RAARF family protein
WALNUT_00008953-RAARF family protein
WALNUT_00012001-RAARF family protein
WALNUT_00013779-RAARF family protein
WALNUT_00015008-RAARF family protein
WALNUT_00015324-RAARF family protein
WALNUT_00018681-RAARF family protein
WALNUT_00022582-RAARF family protein
WALNUT_00022583-RAARF family protein
WALNUT_00025004-RAARF family protein
WALNUT_00025736-RAARF family protein
WALNUT_00027557-RAARF family protein
WALNUT_00031562-RAARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969