PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Ipomoea trifida
EIL Family
Species TF ID Description
Itr_sc000096.1_g00005.1EIL family protein
Itr_sc000141.1_g00080.1EIL family protein
Itr_sc000278.1_g00001.1EIL family protein
Itr_sc000278.1_g00002.1EIL family protein
Itr_sc000422.1_g00014.1EIL family protein
Itr_sc000473.1_g00015.1EIL family protein
Itr_sc000569.1_g00006.1EIL family protein
Itr_sc000592.1_g00023.1EIL family protein
Itr_sc001866.1_g00009.1EIL family protein
Itr_sc003728.1_g00002.1EIL family protein
Itr_sc003822.1_g00001.1EIL family protein
Itr_sc004224.1_g00001.1EIL family protein
Itr_sc006940.1_g00001.1EIL family protein
Itr_sc011389.1_g00001.1EIL family protein
Itr_sc034131.1_g00001.1EIL family protein
Itr_sc043651.1_g00001.1EIL family protein
Itr_sc054378.1_g00001.1EIL family protein
Itr_sc074723.1_g00001.1EIL family protein
EIL Family Introduction

The gaseous phytohormone ethylene regulates various processes related to growth, development, and stress response of higher plants. A largely linear pathway of ethylene signaling was revealed by a number of molecular genetic studies. In the pathway, Ethylene-insensitive3 (EIN3) and EIN3-like (EIL) proteins are the key transcription factors. The EIN3/EIL proteins were shown to regulate expression of the GCC-box-binding transcription factors, ethylene-response factors. It is known that the phenotype of the Arabidopsis thaliana EIN3 (AtEIN3)-deficient mutants, e.g. long seedlings in the presence of ethylene or its precursor, is suppressed by overexpression of Arabidopsis EIL1 (AtEIL1) or EIL2 (AtEIL2), indicating the functional equivalence of these proteins.

In the present study, a region corresponding to the major DBD of the EIN3/EIL transcription factor family, which is the key factor in the ethylene signaling, was identified. The isolated domain exists in a monomeric form and retained the sequence specificity for the DNA binding. The structure determined by NMR spectroscopy consists of five alpha-helices, packing into a novel fold dissimilar to known DBDs. An NMR titration analysis suggested that a region including the key mutation site, ein3-3 site, was shown to be involved in DNA binding.

Yamasaki K, Kigawa T, Inoue M, Yamasaki T, Yabuki T, Aoki M, Seki E, Matsuda T, Tomo Y, Terada T, Shirouzu M, Tanaka A, Seki M, Shinozaki K, Yokoyama S.
Solution structure of the major DNA-binding domain of Arabidopsis thaliana ethylene-insensitive3-like3.
J Mol Biol, 2005. 348(2): p. 253-64.
PMID: 15811366