PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Glycine soja
bHLH Family
Species TF ID Description
KHM98740.1bHLH family protein
KHM98826.1bHLH family protein
KHM99167.1bHLH family protein
KHM99168.1bHLH family protein
KHM99413.1bHLH family protein
KHM99680.1bHLH family protein
KHM99702.1bHLH family protein
KHM99708.1bHLH family protein
KHN00248.1bHLH family protein
KHN00301.1bHLH family protein
KHN00414.1bHLH family protein
KHN00882.1bHLH family protein
KHN00895.1bHLH family protein
KHN01144.1bHLH family protein
KHN01198.1bHLH family protein
KHN01297.1bHLH family protein
KHN01298.1bHLH family protein
KHN01299.1bHLH family protein
KHN01301.1bHLH family protein
KHN01614.1bHLH family protein
KHN01615.1bHLH family protein
KHN01621.1bHLH family protein
KHN01700.1bHLH family protein
KHN01701.1bHLH family protein
KHN01702.1bHLH family protein
KHN02518.1bHLH family protein
KHN02539.1bHLH family protein
KHN02775.1bHLH family protein
KHN02776.1bHLH family protein
KHN03388.1bHLH family protein
KHN03619.1bHLH family protein
KHN03792.1bHLH family protein
KHN03837.1bHLH family protein
KHN03857.1bHLH family protein
KHN04014.1bHLH family protein
KHN04224.1bHLH family protein
KHN04418.1bHLH family protein
KHN04443.1bHLH family protein
KHN04495.1bHLH family protein
KHN04570.1bHLH family protein
KHN04774.1bHLH family protein
KHN04880.1bHLH family protein
KHN04892.1bHLH family protein
KHN04930.1bHLH family protein
KHN05001.1bHLH family protein
KHN05467.1bHLH family protein
KHN05778.1bHLH family protein
KHN05831.1bHLH family protein
KHN05832.1bHLH family protein
KHN05853.1bHLH family protein
KHN05907.1bHLH family protein
KHN06054.1bHLH family protein
KHN06316.1bHLH family protein
KHN06348.1bHLH family protein
KHN06372.1bHLH family protein
KHN06622.1bHLH family protein
KHN06623.1bHLH family protein
KHN06774.1bHLH family protein
KHN06806.1bHLH family protein
KHN06807.1bHLH family protein
KHN06839.1bHLH family protein
KHN06901.1bHLH family protein
KHN07208.1bHLH family protein
KHN07252.1bHLH family protein
KHN07348.1bHLH family protein
KHN07403.1bHLH family protein
KHN07556.1bHLH family protein
KHN07672.1bHLH family protein
KHN07692.1bHLH family protein
KHN07694.1bHLH family protein
KHN07734.1bHLH family protein
KHN07752.1bHLH family protein
KHN08182.1bHLH family protein
KHN08224.1bHLH family protein
KHN08360.1bHLH family protein
KHN08515.1bHLH family protein
KHN08689.1bHLH family protein
KHN08890.1bHLH family protein
KHN08964.1bHLH family protein
KHN09034.1bHLH family protein
KHN09220.1bHLH family protein
KHN09413.1bHLH family protein
KHN09599.1bHLH family protein
KHN09719.1bHLH family protein
KHN09998.1bHLH family protein
KHN10161.1bHLH family protein
KHN10339.1bHLH family protein
KHN10475.1bHLH family protein
KHN10477.1bHLH family protein
KHN10703.1bHLH family protein
KHN10729.1bHLH family protein
KHN10946.1bHLH family protein
KHN11327.1bHLH family protein
KHN11490.1bHLH family protein
KHN11598.1bHLH family protein
KHN11866.1bHLH family protein
KHN12001.1bHLH family protein
KHN12794.1bHLH family protein
KHN13036.1bHLH family protein
KHN13037.1bHLH family protein
KHN13231.1bHLH family protein
KHN13386.1bHLH family protein
KHN13624.1bHLH family protein
KHN14177.1bHLH family protein
KHN14203.1bHLH family protein
KHN14238.1bHLH family protein
KHN14515.1bHLH family protein
KHN14573.1bHLH family protein
KHN14753.1bHLH family protein
KHN14917.1bHLH family protein
KHN14918.1bHLH family protein
KHN15192.1bHLH family protein
KHN15226.1bHLH family protein
KHN15301.1bHLH family protein
KHN15341.1bHLH family protein
KHN15400.1bHLH family protein
KHN15517.1bHLH family protein
KHN15541.1bHLH family protein
KHN15649.1bHLH family protein
KHN15700.1bHLH family protein
KHN15701.1bHLH family protein
KHN15874.1bHLH family protein
KHN15898.1bHLH family protein
KHN15926.1bHLH family protein
KHN16145.1bHLH family protein
KHN16278.1bHLH family protein
KHN16427.1bHLH family protein
KHN16571.1bHLH family protein
KHN16614.1bHLH family protein
KHN16817.1bHLH family protein
KHN16873.1bHLH family protein
KHN16881.1bHLH family protein
KHN17184.1bHLH family protein
KHN17463.1bHLH family protein
KHN17470.1bHLH family protein
KHN17635.1bHLH family protein
KHN17676.1bHLH family protein
KHN17935.1bHLH family protein
KHN18326.1bHLH family protein
KHN18389.1bHLH family protein
KHN18464.1bHLH family protein
KHN18508.1bHLH family protein
KHN18804.1bHLH family protein
KHN18841.1bHLH family protein
KHN18892.1bHLH family protein
KHN19045.1bHLH family protein
KHN19070.1bHLH family protein
KHN19075.1bHLH family protein
KHN19314.1bHLH family protein
KHN19399.1bHLH family protein
KHN19439.1bHLH family protein
KHN19887.1bHLH family protein
KHN20066.1bHLH family protein
KHN20202.1bHLH family protein
KHN20337.1bHLH family protein
KHN20440.1bHLH family protein
KHN20738.1bHLH family protein
KHN20938.1bHLH family protein
KHN21077.1bHLH family protein
KHN21484.1bHLH family protein
KHN21570.1bHLH family protein
KHN21864.1bHLH family protein
KHN21870.1bHLH family protein
KHN21885.1bHLH family protein
KHN22077.1bHLH family protein
KHN22139.1bHLH family protein
KHN22140.1bHLH family protein
KHN22198.1bHLH family protein
KHN22328.1bHLH family protein
KHN22417.1bHLH family protein
KHN22418.1bHLH family protein
KHN22657.1bHLH family protein
KHN23398.1bHLH family protein
KHN23640.1bHLH family protein
KHN23952.1bHLH family protein
KHN24194.1bHLH family protein
KHN24219.1bHLH family protein
KHN25151.1bHLH family protein
KHN25262.1bHLH family protein
KHN25381.1bHLH family protein
KHN25762.1bHLH family protein
KHN25765.1bHLH family protein
KHN25939.1bHLH family protein
KHN26108.1bHLH family protein
KHN26134.1bHLH family protein
KHN26172.1bHLH family protein
KHN26204.1bHLH family protein
KHN26292.1bHLH family protein
KHN26357.1bHLH family protein
KHN26866.1bHLH family protein
KHN26867.1bHLH family protein
KHN26876.1bHLH family protein
KHN27012.1bHLH family protein
KHN27030.1bHLH family protein
KHN27140.1bHLH family protein
KHN27214.1bHLH family protein
KHN27371.1bHLH family protein
KHN27706.1bHLH family protein
KHN27898.1bHLH family protein
KHN27934.1bHLH family protein
KHN27978.1bHLH family protein
KHN27996.1bHLH family protein
KHN28448.1bHLH family protein
KHN28531.1bHLH family protein
KHN28577.1bHLH family protein
KHN28608.1bHLH family protein
KHN28697.1bHLH family protein
KHN28698.1bHLH family protein
KHN28849.1bHLH family protein
KHN28857.1bHLH family protein
KHN28921.1bHLH family protein
KHN29172.1bHLH family protein
KHN29208.1bHLH family protein
KHN29236.1bHLH family protein
KHN29532.1bHLH family protein
KHN29924.1bHLH family protein
KHN29940.1bHLH family protein
KHN30026.1bHLH family protein
KHN30120.1bHLH family protein
KHN30254.1bHLH family protein
KHN30346.1bHLH family protein
KHN30385.1bHLH family protein
KHN30386.1bHLH family protein
KHN30401.1bHLH family protein
KHN30821.1bHLH family protein
KHN30825.1bHLH family protein
KHN30895.1bHLH family protein
KHN31034.1bHLH family protein
KHN31136.1bHLH family protein
KHN31262.1bHLH family protein
KHN31268.1bHLH family protein
KHN31290.1bHLH family protein
KHN31557.1bHLH family protein
KHN31558.1bHLH family protein
KHN31892.1bHLH family protein
KHN31893.1bHLH family protein
KHN31894.1bHLH family protein
KHN32051.1bHLH family protein
KHN32341.1bHLH family protein
KHN32361.1bHLH family protein
KHN32670.1bHLH family protein
KHN32887.1bHLH family protein
KHN33060.1bHLH family protein
KHN33180.1bHLH family protein
KHN33332.1bHLH family protein
KHN33594.1bHLH family protein
KHN33607.1bHLH family protein
KHN33617.1bHLH family protein
KHN33618.1bHLH family protein
KHN33622.1bHLH family protein
KHN33752.1bHLH family protein
KHN34068.1bHLH family protein
KHN34305.1bHLH family protein
KHN34446.1bHLH family protein
KHN35225.1bHLH family protein
KHN35247.1bHLH family protein
KHN35384.1bHLH family protein
KHN35482.1bHLH family protein
KHN35691.1bHLH family protein
KHN35816.1bHLH family protein
KHN35854.1bHLH family protein
KHN36233.1bHLH family protein
KHN36240.1bHLH family protein
KHN36350.1bHLH family protein
KHN36564.1bHLH family protein
KHN36646.1bHLH family protein
KHN36691.1bHLH family protein
KHN36734.1bHLH family protein
KHN36754.1bHLH family protein
KHN36961.1bHLH family protein
KHN36993.1bHLH family protein
KHN37086.1bHLH family protein
KHN37144.1bHLH family protein
KHN37261.1bHLH family protein
KHN37398.1bHLH family protein
KHN37435.1bHLH family protein
KHN37573.1bHLH family protein
KHN37607.1bHLH family protein
KHN37807.1bHLH family protein
KHN37819.1bHLH family protein
KHN38012.1bHLH family protein
KHN38013.1bHLH family protein
KHN38014.1bHLH family protein
KHN38016.1bHLH family protein
KHN38358.1bHLH family protein
KHN38704.1bHLH family protein
KHN38912.1bHLH family protein
KHN38923.1bHLH family protein
KHN39273.1bHLH family protein
KHN39567.1bHLH family protein
KHN39737.1bHLH family protein
KHN39787.1bHLH family protein
KHN39978.1bHLH family protein
KHN40119.1bHLH family protein
KHN40506.1bHLH family protein
KHN40507.1bHLH family protein
KHN40508.1bHLH family protein
KHN40658.1bHLH family protein
KHN41082.1bHLH family protein
KHN41496.1bHLH family protein
KHN41646.1bHLH family protein
KHN42085.1bHLH family protein
KHN42092.1bHLH family protein
KHN42314.1bHLH family protein
KHN42315.1bHLH family protein
KHN42348.1bHLH family protein
KHN42602.1bHLH family protein
KHN42603.1bHLH family protein
KHN42604.1bHLH family protein
KHN43269.1bHLH family protein
KHN43378.1bHLH family protein
KHN43404.1bHLH family protein
KHN43747.1bHLH family protein
KHN43750.1bHLH family protein
KHN43754.1bHLH family protein
KHN44234.1bHLH family protein
KHN44520.1bHLH family protein
KHN44800.1bHLH family protein
KHN44812.1bHLH family protein
KHN44833.1bHLH family protein
KHN44989.1bHLH family protein
KHN45097.1bHLH family protein
KHN45121.1bHLH family protein
KHN45285.1bHLH family protein
KHN45359.1bHLH family protein
KHN45491.1bHLH family protein
KHN45540.1bHLH family protein
KHN45735.1bHLH family protein
KHN46510.1bHLH family protein
KHN46677.1bHLH family protein
KHN47226.1bHLH family protein
KHN47568.1bHLH family protein
KHN47580.1bHLH family protein
KHN47587.1bHLH family protein
KHN47838.1bHLH family protein
KHN47843.1bHLH family protein
KHN48576.1bHLH family protein
KHN48641.1bHLH family protein
KHN48887.1bHLH family protein
KHN48974.1bHLH family protein
KHN49025.1bHLH family protein
KHN49105.1bHLH family protein
bHLH Family Introduction

The basic/helix-loop-helix (bHLH) proteins are a superfamily of transcription factors that have been well characterized in nonplant eukaryotes, especially in mammalian systems, in which considerable structural, functional, and phylogenetic analyses have been performed. The data indicate that bHLH proteins are important regulatory components in transcriptional networks in these systems, controlling a diversity of processes from cell proliferation to cell lineage establishment.

This family is defined by the bHLH signature domain, which consists of 60 amino acids with two functionally distinct regions. The basic region, located at the N-terminal end of the domain, is involved in DNA binding and consists of 15 amino acids with a high number of basic residues. The HLH region, at the C-terminal end, functions as a dimerization domain and is constituted mainly of hydrophobic residues that form two amphipathic -helices separated by a loop region of variable sequence and length. Outside of the conserved bHLH domain, these proteins exhibit considerable sequence divergence. Cocrystal structural analysis has shown that the interaction between the HLH regions of two separate polypeptides leads to the formation of homodimers and/or heterodimers and that the basic region of each partner binds to half of the DNA recognition sequence. Some bHLH proteins form homodimers or restrict their heterodimerization activity to closely related members of the family. On the other hand, some can form heterodimers with one or several different partners.

The core DNA sequence motif recognized by the bHLH proteins is a consensus hexanucleotide sequence known as the E-box (5'-CANNTG-3'). There are different types of E-boxes, depending on the identity of the two central bases. One of the most common is the palindromic G-box (5'-CACGTG-3'). Certain conserved amino acids within the basic region of the protein provide recognition of the core consensus site, whereas other residues in the domain dictate specificity for a given type of E-box . In addition, flanking nucleotides outside of the hexanucleotide core have been shown to play a role in binding specificity, and there is evidence that a loop residue in the protein plays a role in DNA binding through elements that lie outside of the core recognition sequence.

Toledo-Ortiz G, Huq E, Quail PH.
The Arabidopsis basic/helix-loop-helix transcription factor family.
Plant Cell. 2003 Aug;15(8):1749-70
PMID: 12897250