PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Gonium pectorale
MYB Family
Species TF ID Description
KXZ42126.1MYB family protein
KXZ42748.1MYB family protein
KXZ42767.1MYB family protein
KXZ43384.1MYB family protein
KXZ44233.1MYB family protein
KXZ45686.1MYB family protein
KXZ46859.1MYB family protein
KXZ46891.1MYB family protein
KXZ51003.1MYB family protein
KXZ52260.1MYB family protein
KXZ54653.1MYB family protein
KXZ55380.1MYB family protein
MYB Family Introduction

MYB factors represent a family of proteins that include the conserved MYB DNA-binding domain.The first MYB gene identified was the "oncogene" v-Myb derived from the avian myeloblastosis virus . Evidence obtained from sequence comparisons indicates that v-Myb may have originated from a vertebrate gene, which mutated once it became part of the virus. Many vertebrates contain three genes related to v-Myb c-Myb, A-Myb and B-Myb and other similar genes have been identified in insects, plants, fungi and slime moulds. The encoded proteins are crucial to the control of proliferation and differentiation in a number of cell types, and share the conserved MYB DNA-binding domain. This domain generally comprises up to three imperfect repeats, each forming a helix-turn-helix structure of about 53 amino acids. Three regularly spaced tryptophan residues, which form a tryptophan cluster in the three-dimensional helix-turn-helix structure, are characteristic of a MYB repeat. The three repeats in c-Myb are referred to as R1, R2 and R3; and repeats from other MYB proteins are categorised according to their similarity to either R1, R2 or R3.

In contrast to animals, plants contain a MYB-protein subfamily that is characterised by the R2R3-type MYB domain. MYB proteins can be classified into three subfamilies depending on the number of adjacent repeats in the MYB domain (one, two or three). We refer to MYB-like proteins with one repeat as "MYB1R factors", with two as "R2R3-type MYB" factors, and with three repeats as "MYB3R" factors.

Stracke R, Werber M, Weisshaar B.
The R2R3-MYB gene family in Arabidopsis thaliana.
Curr Opin Plant Biol. 2001 Oct;4(5):447-56. Review.
PMID: 11597504