PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Gossypium hirsutum
WRKY Family
Species TF ID Description
Gh_A01G0639WRKY family protein
Gh_A01G0681WRKY family protein
Gh_A01G1273WRKY family protein
Gh_A01G1477WRKY family protein
Gh_A02G0029WRKY family protein
Gh_A02G0541WRKY family protein
Gh_A02G1042WRKY family protein
Gh_A02G1301WRKY family protein
Gh_A02G1304WRKY family protein
Gh_A02G1488WRKY family protein
Gh_A03G0210WRKY family protein
Gh_A03G1081WRKY family protein
Gh_A03G2109WRKY family protein
Gh_A04G0658WRKY family protein
Gh_A04G0709WRKY family protein
Gh_A04G1269WRKY family protein
Gh_A05G0483WRKY family protein
Gh_A05G0484WRKY family protein
Gh_A05G0528WRKY family protein
Gh_A05G1019WRKY family protein
Gh_A05G1264WRKY family protein
Gh_A05G1287WRKY family protein
Gh_A05G1472WRKY family protein
Gh_A05G1774WRKY family protein
Gh_A05G2091WRKY family protein
Gh_A05G2237WRKY family protein
Gh_A05G2378WRKY family protein
Gh_A05G2938WRKY family protein
Gh_A05G3158WRKY family protein
Gh_A05G3186WRKY family protein
Gh_A05G3283WRKY family protein
Gh_A05G3382WRKY family protein
Gh_A05G3498WRKY family protein
Gh_A05G3499WRKY family protein
Gh_A05G3887WRKY family protein
Gh_A06G0179WRKY family protein
Gh_A06G0764WRKY family protein
Gh_A06G0879WRKY family protein
Gh_A06G0917WRKY family protein
Gh_A06G1167WRKY family protein
Gh_A06G1188WRKY family protein
Gh_A06G1322WRKY family protein
Gh_A06G1585WRKY family protein
Gh_A06G1923WRKY family protein
Gh_A06G2115WRKY family protein
Gh_A06G2118WRKY family protein
Gh_A07G0017WRKY family protein
Gh_A07G0212WRKY family protein
Gh_A07G0261WRKY family protein
Gh_A07G0263WRKY family protein
Gh_A07G0441WRKY family protein
Gh_A07G1198WRKY family protein
Gh_A07G1274WRKY family protein
Gh_A07G1524WRKY family protein
Gh_A07G1665WRKY family protein
Gh_A07G1892WRKY family protein
Gh_A07G1912WRKY family protein
Gh_A07G2119WRKY family protein
Gh_A07G2274WRKY family protein
Gh_A07G2317WRKY family protein
Gh_A08G0212WRKY family protein
Gh_A08G0526WRKY family protein
Gh_A08G1051WRKY family protein
Gh_A08G1141WRKY family protein
Gh_A08G1191WRKY family protein
Gh_A08G1256WRKY family protein
Gh_A08G1540WRKY family protein
Gh_A08G1914WRKY family protein
Gh_A08G2417WRKY family protein
Gh_A08G2488WRKY family protein
Gh_A09G0070WRKY family protein
Gh_A09G0118WRKY family protein
Gh_A09G0225WRKY family protein
Gh_A09G0361WRKY family protein
Gh_A09G1447WRKY family protein
Gh_A09G2126WRKY family protein
Gh_A10G0054WRKY family protein
Gh_A10G0113WRKY family protein
Gh_A10G0323WRKY family protein
Gh_A10G0359WRKY family protein
Gh_A10G0638WRKY family protein
Gh_A10G0753WRKY family protein
Gh_A10G1549WRKY family protein
Gh_A11G0103WRKY family protein
Gh_A11G0118WRKY family protein
Gh_A11G0833WRKY family protein
Gh_A11G0834WRKY family protein
Gh_A11G0868WRKY family protein
Gh_A11G0954WRKY family protein
Gh_A11G0984WRKY family protein
Gh_A11G0997WRKY family protein
Gh_A11G1172WRKY family protein
Gh_A11G1391WRKY family protein
Gh_A11G1432WRKY family protein
Gh_A11G1801WRKY family protein
Gh_A11G1811WRKY family protein
Gh_A11G2016WRKY family protein
Gh_A11G2258WRKY family protein
Gh_A12G0294WRKY family protein
Gh_A12G0887WRKY family protein
Gh_A12G1084WRKY family protein
Gh_A12G1116WRKY family protein
Gh_A12G1124WRKY family protein
Gh_A12G1488WRKY family protein
Gh_A12G1594WRKY family protein
Gh_A12G1670WRKY family protein
Gh_A12G2121WRKY family protein
Gh_A12G2292WRKY family protein
Gh_A12G2671WRKY family protein
Gh_A13G0059WRKY family protein
Gh_A13G0630WRKY family protein
Gh_A13G0696WRKY family protein
Gh_A13G0715WRKY family protein
Gh_A13G1138WRKY family protein
Gh_A13G1330WRKY family protein
Gh_D01G0657WRKY family protein
Gh_D01G0702WRKY family protein
Gh_D01G1493WRKY family protein
Gh_D01G1714WRKY family protein
Gh_D02G0043WRKY family protein
Gh_D02G0605WRKY family protein
Gh_D02G1291WRKY family protein
Gh_D02G1493WRKY family protein
Gh_D03G0226WRKY family protein
Gh_D03G0441WRKY family protein
Gh_D03G0444WRKY family protein
Gh_D03G0682WRKY family protein
Gh_D03G1371WRKY family protein
Gh_D04G0112WRKY family protein
Gh_D04G0113WRKY family protein
Gh_D04G0203WRKY family protein
Gh_D04G0323WRKY family protein
Gh_D04G0418WRKY family protein
Gh_D04G0470WRKY family protein
Gh_D04G0725WRKY family protein
Gh_D04G1122WRKY family protein
Gh_D04G1177WRKY family protein
Gh_D04G1318WRKY family protein
Gh_D04G1896WRKY family protein
Gh_D05G0600WRKY family protein
Gh_D05G0601WRKY family protein
Gh_D05G0648WRKY family protein
Gh_D05G1063WRKY family protein
Gh_D05G1137WRKY family protein
Gh_D05G1432WRKY family protein
Gh_D05G1645WRKY family protein
Gh_D05G1968WRKY family protein
Gh_D05G2344WRKY family protein
Gh_D05G2499WRKY family protein
Gh_D05G2642WRKY family protein
Gh_D05G3827WRKY family protein
Gh_D06G0174WRKY family protein
Gh_D06G0175WRKY family protein
Gh_D06G1029WRKY family protein
Gh_D06G1078WRKY family protein
Gh_D06G1082WRKY family protein
Gh_D06G1121WRKY family protein
Gh_D06G1196WRKY family protein
Gh_D06G1453WRKY family protein
Gh_D06G1486WRKY family protein
Gh_D06G1651WRKY family protein
Gh_D06G1939WRKY family protein
Gh_D06G1966WRKY family protein
Gh_D06G2328WRKY family protein
Gh_D07G0023WRKY family protein
Gh_D07G0177WRKY family protein
Gh_D07G0267WRKY family protein
Gh_D07G0317WRKY family protein
Gh_D07G0318WRKY family protein
Gh_D07G0505WRKY family protein
Gh_D07G0824WRKY family protein
Gh_D07G1299WRKY family protein
Gh_D07G1384WRKY family protein
Gh_D07G1672WRKY family protein
Gh_D07G1877WRKY family protein
Gh_D07G2107WRKY family protein
Gh_D07G2135WRKY family protein
Gh_D07G2328WRKY family protein
Gh_D08G0290WRKY family protein
Gh_D08G0306WRKY family protein
Gh_D08G0620WRKY family protein
Gh_D08G1232WRKY family protein
Gh_D08G1333WRKY family protein
Gh_D08G1424WRKY family protein
Gh_D08G1474WRKY family protein
Gh_D08G1543WRKY family protein
Gh_D08G1841WRKY family protein
Gh_D08G2032WRKY family protein
Gh_D08G2279WRKY family protein
Gh_D09G0067WRKY family protein
Gh_D09G0113WRKY family protein
Gh_D09G0213WRKY family protein
Gh_D09G0376WRKY family protein
Gh_D09G1456WRKY family protein
Gh_D09G2332WRKY family protein
Gh_D10G0061WRKY family protein
Gh_D10G0117WRKY family protein
Gh_D10G0329WRKY family protein
Gh_D10G0367WRKY family protein
Gh_D10G0757WRKY family protein
Gh_D10G1011WRKY family protein
Gh_D10G1797WRKY family protein
Gh_D11G0118WRKY family protein
Gh_D11G0132WRKY family protein
Gh_D11G0976WRKY family protein
Gh_D11G0977WRKY family protein
Gh_D11G1011WRKY family protein
Gh_D11G1099WRKY family protein
Gh_D11G1141WRKY family protein
Gh_D11G1328WRKY family protein
Gh_D11G1536WRKY family protein
Gh_D11G1584WRKY family protein
Gh_D11G1963WRKY family protein
Gh_D11G2246WRKY family protein
Gh_D11G2566WRKY family protein
Gh_D12G0371WRKY family protein
Gh_D12G0971WRKY family protein
Gh_D12G1207WRKY family protein
Gh_D12G1243WRKY family protein
Gh_D12G1253WRKY family protein
Gh_D12G1614WRKY family protein
Gh_D12G1734WRKY family protein
Gh_D12G1827WRKY family protein
Gh_D12G2301WRKY family protein
Gh_D12G2429WRKY family protein
Gh_D12G2748WRKY family protein
Gh_D13G0071WRKY family protein
Gh_D13G0744WRKY family protein
Gh_D13G0820WRKY family protein
Gh_D13G0837WRKY family protein
Gh_D13G1418WRKY family protein
Gh_D13G1636WRKY family protein
Gh_Sca005564G01WRKY family protein
Gh_Sca005611G01WRKY family protein
Gh_Sca005611G02WRKY family protein
Gh_Sca005978G01WRKY family protein
Gh_Sca009206G01WRKY family protein
Gh_Sca204211G01WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701