PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Gossypium hirsutum
SRS Family
Species TF ID Description
Gh_A01G0919SRS family protein
Gh_A02G1614SRS family protein
Gh_A03G0715SRS family protein
Gh_A03G1745SRS family protein
Gh_A05G0591SRS family protein
Gh_A05G1619SRS family protein
Gh_A07G1091SRS family protein
Gh_A08G2528SRS family protein
Gh_A09G1024SRS family protein
Gh_A10G1664SRS family protein
Gh_A11G1652SRS family protein
Gh_A13G0285SRS family protein
Gh_D01G0956SRS family protein
Gh_D02G0968SRS family protein
Gh_D02G2179SRS family protein
Gh_D03G0108SRS family protein
Gh_D05G0721SRS family protein
Gh_D05G1803SRS family protein
Gh_D06G0025SRS family protein
Gh_D07G1191SRS family protein
Gh_D08G0138SRS family protein
Gh_D09G1045SRS family protein
Gh_D10G1921SRS family protein
Gh_D11G1809SRS family protein
Gh_D13G0304SRS family protein
SRS Family Introduction

SHI RELATED SEQUENCE(SRS), which encode proteins with a single zinc finger motif. The genes are members of a small gene family of putative transcription factors in which the SHORT INTERNODES (SHI) gene is found.

The predicted amino acid sequence of SHI has acidic and glutamine-rich stretches and shows sequence similarity over a putative zinc finger region to three presumptive Arabidopsis proteins. This suggests that SHI may act as a negative regulator of GA responses through transcriptional control.

The predicted SHI protein consists of 331 amino acids. A region containing six cysteine residues (amino acids 120 to 147) in a C-X2-C-X7-C-X4-C-X2-C-X7-C arrangement (where X is a variable amino acid) is suggested to make up a zinc finger domain similar to the Zn2Cys6 cluster found in the DNA binding region of the yeast transcriptional activator GAL4 (Kraulis et al. 1992 ). Two regions rich in glutamine residues were found adjacent to the zinc finger domain, as well as a short stretch of acidic residues in the C-terminal third of the SHI protein. These features have been found in transcription factor proteins and have been demonstrated to be important for their function as transcriptional activators (Mitchell and Tjian 1989 ). Furthermore, two putative nuclear localization signals (NLSs) were found in the SHI sequence. These are two basic stretches (amino acids 160 to 165 and 183 to 188) that conform to the consensus of the simian virus 40-like "typical NLS" defined as four arginines and lysines within a region of six amino acids (Boulikas 1994 ; LaCasse and Lefebvre 1995 ).

Fridborg I, Kuusk S, Moritz T, Sundberg E.
The Arabidopsis dwarf mutant shi exhibits reduced gibberellin responses conferred by overexpression of a new putative zinc finger protein.
Plant Cell. 1999 Jun;11(6):1019-32.