Plant Transcription Factor Database
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Gossypium hirsutum
NF-YC Family
Species TF ID Description
Gh_A01G0796NF-YC family protein
Gh_A02G0284NF-YC family protein
Gh_A03G1101NF-YC family protein
Gh_A05G0608NF-YC family protein
Gh_A05G3429NF-YC family protein
Gh_A06G1536NF-YC family protein
Gh_A07G0449NF-YC family protein
Gh_A07G1071NF-YC family protein
Gh_A08G1630NF-YC family protein
Gh_A08G1872NF-YC family protein
Gh_A11G2393NF-YC family protein
Gh_A11G2618NF-YC family protein
Gh_A12G0509NF-YC family protein
Gh_A12G1722NF-YC family protein
Gh_D01G0824NF-YC family protein
Gh_D02G0349NF-YC family protein
Gh_D02G1526NF-YC family protein
Gh_D04G0158NF-YC family protein
Gh_D05G0739NF-YC family protein
Gh_D06G1906NF-YC family protein
Gh_D07G0513NF-YC family protein
Gh_D07G1166NF-YC family protein
Gh_D08G1942NF-YC family protein
Gh_D08G2234NF-YC family protein
Gh_D11G2708NF-YC family protein
Gh_D11G2928NF-YC family protein
Gh_D12G0521NF-YC family protein
Gh_D12G1881NF-YC family protein
Gh_Sca145821G01NF-YC family protein
Gh_Sca187117G01NF-YC family protein
NF-YC Family Introduction

NF-Y transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NF-Y transcription factor complex is composed of three unique subunits: NF-YA, NF-YB, and NF-YC. Assembly of the NF-Y heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NF-YB and NF-YC. This dimer then translocates to the nucleus, where the third subunit, NF-YA, is recruited to generate the mature, heterotrimeric NF-Y transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NF-Y binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).

As with NF-YA, NF-YB and NF-YC families have well-described subunit interaction and DNA-binding domains ( Kim et al., 1996; Sinha et al., 1996; McNabb et al., 1997; Romier et al., 2003). The conserved regions of NF-YB and NF-YC have structural and amino acid homology to histone fold motifs. Specifically, NF-YB is related to the histone fold motifs of H2B histones, while NF-YC subunits are related to H2A histones (Mantovani, 1999).

Siefers N, Dang KK, Kumimoto RW, Bynum WE 4th, Tayrose G, Holt BF 3rd.
Tissue-specific expression patterns of Arabidopsis NF-Y transcription factors suggest potential for extensive combinatorial complexity.
Plant Physiol, 2009. 149(2): p. 625-41.
PMID: 19019982