PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Gossypium hirsutum
E2F/DP Family
Species TF ID Description
Gh_A01G1831E2F/DP family protein
Gh_A01G2098E2F/DP family protein
Gh_A07G1021E2F/DP family protein
Gh_A08G0857E2F/DP family protein
Gh_A09G0237E2F/DP family protein
Gh_A09G0927E2F/DP family protein
Gh_A09G1373E2F/DP family protein
Gh_A11G2912E2F/DP family protein
Gh_A13G1929E2F/DP family protein
Gh_D01G1236E2F/DP family protein
Gh_D01G2069E2F/DP family protein
Gh_D07G1097E2F/DP family protein
Gh_D08G1034E2F/DP family protein
Gh_D09G0232E2F/DP family protein
Gh_D09G0956E2F/DP family protein
Gh_D09G1374E2F/DP family protein
Gh_D11G3298E2F/DP family protein
Gh_D13G2317E2F/DP family protein
Gh_Sca005145G01E2F/DP family protein
E2F/DP Family Introduction

E2F transcription factors are a family of proteins that share a related DNA-binding domain and that bind to overlapping sets of target promoters. Most E2F proteins associate with a DP protein and form heterodimeric complexes that bind to DNA in a sequence-specific manner. E2F proteins control the temporal expression of genes that are needed for multiple processes during the cell cycle. Consequently, the level of E2F-dependent transcription is important for cell proliferation.

Different types of E2F complexes either activate or repress transcription. E2F repressor complexes suppress the transcription of their targets in quiescent cells, in differentiated cells and during the G1 phase of the cell cycle. When cells enter the cell cycle and proliferate, these repressors are disrupted and/or replaced by activator forms of E2F that promote gene expression.

van den Heuvel S, Dyson NJ.
Conserved functions of the pRB and E2F families.
Nat Rev Mol Cell Biol, 2008. 9(9): p. 713-24.
PMID: 18719710