PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Gossypium hirsutum
AP2 Family
Species TF ID Description
Gh_A01G1867AP2 family protein
Gh_A02G1392AP2 family protein
Gh_A02G1495AP2 family protein
Gh_A03G0292AP2 family protein
Gh_A04G1351AP2 family protein
Gh_A05G0024AP2 family protein
Gh_A05G0861AP2 family protein
Gh_A05G0999AP2 family protein
Gh_A05G3160AP2 family protein
Gh_A05G3514AP2 family protein
Gh_A06G0222AP2 family protein
Gh_A07G1138AP2 family protein
Gh_A07G1973AP2 family protein
Gh_A08G0751AP2 family protein
Gh_A08G2008AP2 family protein
Gh_A08G2566AP2 family protein
Gh_A09G0218AP2 family protein
Gh_A09G0219AP2 family protein
Gh_A09G1077AP2 family protein
Gh_A10G0792AP2 family protein
Gh_A10G1731AP2 family protein
Gh_A11G1795AP2 family protein
Gh_A11G1920AP2 family protein
Gh_A11G2782AP2 family protein
Gh_A12G0670AP2 family protein
Gh_A12G0721AP2 family protein
Gh_A12G1529AP2 family protein
Gh_A12G2200AP2 family protein
Gh_D01G2112AP2 family protein
Gh_D03G0218AP2 family protein
Gh_D03G0331AP2 family protein
Gh_D04G0094AP2 family protein
Gh_D04G0466AP2 family protein
Gh_D04G0842AP2 family protein
Gh_D05G0071AP2 family protein
Gh_D05G1117AP2 family protein
Gh_D05G3873AP2 family protein
Gh_D06G0216AP2 family protein
Gh_D07G1235AP2 family protein
Gh_D08G0014AP2 family protein
Gh_D08G0894AP2 family protein
Gh_D08G2402AP2 family protein
Gh_D09G0206AP2 family protein
Gh_D09G1085AP2 family protein
Gh_D10G0971AP2 family protein
Gh_D10G2551AP2 family protein
Gh_D11G1956AP2 family protein
Gh_D11G2055AP2 family protein
Gh_D11G3121AP2 family protein
Gh_D12G0675AP2 family protein
Gh_D12G0743AP2 family protein
Gh_D12G1652AP2 family protein
Gh_A10G1860AP2 family protein
Gh_D03G0620AP2 family protein
Gh_D10G2123AP2 family protein
Gh_A02G1061AP2 family protein
Gh_D10G0938AP2 family protein
Gh_A10G0822AP2 family protein
Gh_D07G2191AP2 family protein
AP2 Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

Genes in the AP2 family have been shown to participate in the regulation of developmental processes, e.g. flower development, spikelet meristem determinacy, leaf epidermal cell identity, and embryo development.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444


Using an in vitro selection procedure, the DNA binding specificity of the two AP2 repeat containing protein ANT was found to be 5'-gCAC(A/G)N(A/T)TcCC(a/g)ANG(c/t)-3'. This consensus site is much longer than sites recognized by proteins containing a single AP2 repeat and neither AP2 repeat of ANT was alone capable of binding to the selected sequences, suggesting that both AP2 repeats make DNA contacts.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102