Plant Transcription Factor Database
Previous version: v1.0, v2.0, v3.0
Genlisea aurea
WRKY Family
Species TF ID Description
EPS57629.1WRKY family protein
EPS57757.1WRKY family protein
EPS58266.1WRKY family protein
EPS58686.1WRKY family protein
EPS58967.1WRKY family protein
EPS59077.1WRKY family protein
EPS59220.1WRKY family protein
EPS59366.1WRKY family protein
EPS59589.1WRKY family protein
EPS60069.1WRKY family protein
EPS60198.1WRKY family protein
EPS60392.1WRKY family protein
EPS60712.1WRKY family protein
EPS60964.1WRKY family protein
EPS61412.1WRKY family protein
EPS62848.1WRKY family protein
EPS63650.1WRKY family protein
EPS63866.1WRKY family protein
EPS65077.1WRKY family protein
EPS65189.1WRKY family protein
EPS66072.1WRKY family protein
EPS66166.1WRKY family protein
EPS66178.1WRKY family protein
EPS66481.1WRKY family protein
EPS66490.1WRKY family protein
EPS66609.1WRKY family protein
EPS66831.1WRKY family protein
EPS67450.1WRKY family protein
EPS67750.1WRKY family protein
EPS68080.1WRKY family protein
EPS68652.1WRKY family protein
EPS69684.1WRKY family protein
EPS70083.1WRKY family protein
EPS71097.1WRKY family protein
EPS71531.1WRKY family protein
EPS71772.1WRKY family protein
EPS71773.1WRKY family protein
EPS74429.1WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701