PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Gossypium arboreum
bHLH Family
Species TF ID Description
Cotton_A_00097_BGI-A2_v1.0bHLH family protein
Cotton_A_00658_BGI-A2_v1.0bHLH family protein
Cotton_A_00736_BGI-A2_v1.0bHLH family protein
Cotton_A_00932_BGI-A2_v1.0bHLH family protein
Cotton_A_01066_BGI-A2_v1.0bHLH family protein
Cotton_A_01078_BGI-A2_v1.0bHLH family protein
Cotton_A_01249_BGI-A2_v1.0bHLH family protein
Cotton_A_01362_BGI-A2_v1.0bHLH family protein
Cotton_A_01363_BGI-A2_v1.0bHLH family protein
Cotton_A_01558_BGI-A2_v1.0bHLH family protein
Cotton_A_01739_BGI-A2_v1.0bHLH family protein
Cotton_A_01907_BGI-A2_v1.0bHLH family protein
Cotton_A_01949_BGI-A2_v1.0bHLH family protein
Cotton_A_01954_BGI-A2_v1.0bHLH family protein
Cotton_A_02794_BGI-A2_v1.0bHLH family protein
Cotton_A_02971_BGI-A2_v1.0bHLH family protein
Cotton_A_03298_BGI-A2_v1.0bHLH family protein
Cotton_A_03457_BGI-A2_v1.0bHLH family protein
Cotton_A_03562_BGI-A2_v1.0bHLH family protein
Cotton_A_03649_BGI-A2_v1.0bHLH family protein
Cotton_A_03791_BGI-A2_v1.0bHLH family protein
Cotton_A_03906_BGI-A2_v1.0bHLH family protein
Cotton_A_03966_BGI-A2_v1.0bHLH family protein
Cotton_A_04392_BGI-A2_v1.0bHLH family protein
Cotton_A_04445_BGI-A2_v1.0bHLH family protein
Cotton_A_04469_BGI-A2_v1.0bHLH family protein
Cotton_A_04711_BGI-A2_v1.0bHLH family protein
Cotton_A_04718_BGI-A2_v1.0bHLH family protein
Cotton_A_05668_BGI-A2_v1.0bHLH family protein
Cotton_A_05723_BGI-A2_v1.0bHLH family protein
Cotton_A_05880_BGI-A2_v1.0bHLH family protein
Cotton_A_05966_BGI-A2_v1.0bHLH family protein
Cotton_A_06141_BGI-A2_v1.0bHLH family protein
Cotton_A_06213_BGI-A2_v1.0bHLH family protein
Cotton_A_06612_BGI-A2_v1.0bHLH family protein
Cotton_A_06817_BGI-A2_v1.0bHLH family protein
Cotton_A_07316_BGI-A2_v1.0bHLH family protein
Cotton_A_07321_BGI-A2_v1.0bHLH family protein
Cotton_A_07409_BGI-A2_v1.0bHLH family protein
Cotton_A_07590_BGI-A2_v1.0bHLH family protein
Cotton_A_07705_BGI-A2_v1.0bHLH family protein
Cotton_A_07788_BGI-A2_v1.0bHLH family protein
Cotton_A_07791_BGI-A2_v1.0bHLH family protein
Cotton_A_07854_BGI-A2_v1.0bHLH family protein
Cotton_A_07908_BGI-A2_v1.0bHLH family protein
Cotton_A_07914_BGI-A2_v1.0bHLH family protein
Cotton_A_08002_BGI-A2_v1.0bHLH family protein
Cotton_A_08234_BGI-A2_v1.0bHLH family protein
Cotton_A_08370_BGI-A2_v1.0bHLH family protein
Cotton_A_08659_BGI-A2_v1.0bHLH family protein
Cotton_A_08669_BGI-A2_v1.0bHLH family protein
Cotton_A_08820_BGI-A2_v1.0bHLH family protein
Cotton_A_08943_BGI-A2_v1.0bHLH family protein
Cotton_A_09193_BGI-A2_v1.0bHLH family protein
Cotton_A_09215_BGI-A2_v1.0bHLH family protein
Cotton_A_09216_BGI-A2_v1.0bHLH family protein
Cotton_A_09219_BGI-A2_v1.0bHLH family protein
Cotton_A_09305_BGI-A2_v1.0bHLH family protein
Cotton_A_09361_BGI-A2_v1.0bHLH family protein
Cotton_A_09442_BGI-A2_v1.0bHLH family protein
Cotton_A_09661_BGI-A2_v1.0bHLH family protein
Cotton_A_10140_BGI-A2_v1.0bHLH family protein
Cotton_A_10345_BGI-A2_v1.0bHLH family protein
Cotton_A_10840_BGI-A2_v1.0bHLH family protein
Cotton_A_10855_BGI-A2_v1.0bHLH family protein
Cotton_A_11175_BGI-A2_v1.0bHLH family protein
Cotton_A_11194_BGI-A2_v1.0bHLH family protein
Cotton_A_11283_BGI-A2_v1.0bHLH family protein
Cotton_A_12235_BGI-A2_v1.0bHLH family protein
Cotton_A_13206_BGI-A2_v1.0bHLH family protein
Cotton_A_13783_BGI-A2_v1.0bHLH family protein
Cotton_A_13784_BGI-A2_v1.0bHLH family protein
Cotton_A_13785_BGI-A2_v1.0bHLH family protein
Cotton_A_14067_BGI-A2_v1.0bHLH family protein
Cotton_A_14075_BGI-A2_v1.0bHLH family protein
Cotton_A_14191_BGI-A2_v1.0bHLH family protein
Cotton_A_14312_BGI-A2_v1.0bHLH family protein
Cotton_A_14318_BGI-A2_v1.0bHLH family protein
Cotton_A_14405_BGI-A2_v1.0bHLH family protein
Cotton_A_14739_BGI-A2_v1.0bHLH family protein
Cotton_A_14779_BGI-A2_v1.0bHLH family protein
Cotton_A_14790_BGI-A2_v1.0bHLH family protein
Cotton_A_14845_BGI-A2_v1.0bHLH family protein
Cotton_A_14902_BGI-A2_v1.0bHLH family protein
Cotton_A_14914_BGI-A2_v1.0bHLH family protein
Cotton_A_15200_BGI-A2_v1.0bHLH family protein
Cotton_A_15254_BGI-A2_v1.0bHLH family protein
Cotton_A_15346_BGI-A2_v1.0bHLH family protein
Cotton_A_15348_BGI-A2_v1.0bHLH family protein
Cotton_A_15447_BGI-A2_v1.0bHLH family protein
Cotton_A_15640_BGI-A2_v1.0bHLH family protein
Cotton_A_15654_BGI-A2_v1.0bHLH family protein
Cotton_A_15656_BGI-A2_v1.0bHLH family protein
Cotton_A_15701_BGI-A2_v1.0bHLH family protein
Cotton_A_16694_BGI-A2_v1.0bHLH family protein
Cotton_A_16748_BGI-A2_v1.0bHLH family protein
Cotton_A_16840_BGI-A2_v1.0bHLH family protein
Cotton_A_17293_BGI-A2_v1.0bHLH family protein
Cotton_A_17491_BGI-A2_v1.0bHLH family protein
Cotton_A_17640_BGI-A2_v1.0bHLH family protein
Cotton_A_17744_BGI-A2_v1.0bHLH family protein
Cotton_A_17918_BGI-A2_v1.0bHLH family protein
Cotton_A_18661_BGI-A2_v1.0bHLH family protein
Cotton_A_18709_BGI-A2_v1.0bHLH family protein
Cotton_A_18878_BGI-A2_v1.0bHLH family protein
Cotton_A_19100_BGI-A2_v1.0bHLH family protein
Cotton_A_19301_BGI-A2_v1.0bHLH family protein
Cotton_A_19366_BGI-A2_v1.0bHLH family protein
Cotton_A_19391_BGI-A2_v1.0bHLH family protein
Cotton_A_19428_BGI-A2_v1.0bHLH family protein
Cotton_A_19514_BGI-A2_v1.0bHLH family protein
Cotton_A_19549_BGI-A2_v1.0bHLH family protein
Cotton_A_19722_BGI-A2_v1.0bHLH family protein
Cotton_A_20686_BGI-A2_v1.0bHLH family protein
Cotton_A_20785_BGI-A2_v1.0bHLH family protein
Cotton_A_20787_BGI-A2_v1.0bHLH family protein
Cotton_A_20980_BGI-A2_v1.0bHLH family protein
Cotton_A_21074_BGI-A2_v1.0bHLH family protein
Cotton_A_21075_BGI-A2_v1.0bHLH family protein
Cotton_A_21315_BGI-A2_v1.0bHLH family protein
Cotton_A_21341_BGI-A2_v1.0bHLH family protein
Cotton_A_21539_BGI-A2_v1.0bHLH family protein
Cotton_A_21593_BGI-A2_v1.0bHLH family protein
Cotton_A_21667_BGI-A2_v1.0bHLH family protein
Cotton_A_21720_BGI-A2_v1.0bHLH family protein
Cotton_A_22395_BGI-A2_v1.0bHLH family protein
Cotton_A_22712_BGI-A2_v1.0bHLH family protein
Cotton_A_23045_BGI-A2_v1.0bHLH family protein
Cotton_A_23093_BGI-A2_v1.0bHLH family protein
Cotton_A_23114_BGI-A2_v1.0bHLH family protein
Cotton_A_23495_BGI-A2_v1.0bHLH family protein
Cotton_A_23641_BGI-A2_v1.0bHLH family protein
Cotton_A_23759_BGI-A2_v1.0bHLH family protein
Cotton_A_24114_BGI-A2_v1.0bHLH family protein
Cotton_A_24348_BGI-A2_v1.0bHLH family protein
Cotton_A_24360_BGI-A2_v1.0bHLH family protein
Cotton_A_24448_BGI-A2_v1.0bHLH family protein
Cotton_A_24713_BGI-A2_v1.0bHLH family protein
Cotton_A_24786_BGI-A2_v1.0bHLH family protein
Cotton_A_24931_BGI-A2_v1.0bHLH family protein
Cotton_A_25003_BGI-A2_v1.0bHLH family protein
Cotton_A_25051_BGI-A2_v1.0bHLH family protein
Cotton_A_25258_BGI-A2_v1.0bHLH family protein
Cotton_A_25894_BGI-A2_v1.0bHLH family protein
Cotton_A_25970_BGI-A2_v1.0bHLH family protein
Cotton_A_26005_BGI-A2_v1.0bHLH family protein
Cotton_A_26093_BGI-A2_v1.0bHLH family protein
Cotton_A_26571_BGI-A2_v1.0bHLH family protein
Cotton_A_27088_BGI-A2_v1.0bHLH family protein
Cotton_A_27326_BGI-A2_v1.0bHLH family protein
Cotton_A_27359_BGI-A2_v1.0bHLH family protein
Cotton_A_27688_BGI-A2_v1.0bHLH family protein
Cotton_A_27791_BGI-A2_v1.0bHLH family protein
Cotton_A_27862_BGI-A2_v1.0bHLH family protein
Cotton_A_27959_BGI-A2_v1.0bHLH family protein
Cotton_A_28479_BGI-A2_v1.0bHLH family protein
Cotton_A_28763_BGI-A2_v1.0bHLH family protein
Cotton_A_29014_BGI-A2_v1.0bHLH family protein
Cotton_A_29614_BGI-A2_v1.0bHLH family protein
Cotton_A_29708_BGI-A2_v1.0bHLH family protein
Cotton_A_29754_BGI-A2_v1.0bHLH family protein
Cotton_A_29801_BGI-A2_v1.0bHLH family protein
Cotton_A_29902_BGI-A2_v1.0bHLH family protein
Cotton_A_29912_BGI-A2_v1.0bHLH family protein
Cotton_A_29913_BGI-A2_v1.0bHLH family protein
Cotton_A_29988_BGI-A2_v1.0bHLH family protein
Cotton_A_30335_BGI-A2_v1.0bHLH family protein
Cotton_A_30567_BGI-A2_v1.0bHLH family protein
Cotton_A_30832_BGI-A2_v1.0bHLH family protein
Cotton_A_31085_BGI-A2_v1.0bHLH family protein
Cotton_A_31202_BGI-A2_v1.0bHLH family protein
Cotton_A_31550_BGI-A2_v1.0bHLH family protein
Cotton_A_32486_BGI-A2_v1.0bHLH family protein
Cotton_A_32545_BGI-A2_v1.0bHLH family protein
Cotton_A_32570_BGI-A2_v1.0bHLH family protein
Cotton_A_32765_BGI-A2_v1.0bHLH family protein
Cotton_A_32766_BGI-A2_v1.0bHLH family protein
Cotton_A_32829_BGI-A2_v1.0bHLH family protein
Cotton_A_32830_BGI-A2_v1.0bHLH family protein
Cotton_A_33275_BGI-A2_v1.0bHLH family protein
Cotton_A_33827_BGI-A2_v1.0bHLH family protein
Cotton_A_33834_BGI-A2_v1.0bHLH family protein
Cotton_A_34261_BGI-A2_v1.0bHLH family protein
Cotton_A_34289_BGI-A2_v1.0bHLH family protein
Cotton_A_34418_BGI-A2_v1.0bHLH family protein
Cotton_A_34462_BGI-A2_v1.0bHLH family protein
Cotton_A_34469_BGI-A2_v1.0bHLH family protein
Cotton_A_34746_BGI-A2_v1.0bHLH family protein
Cotton_A_34907_BGI-A2_v1.0bHLH family protein
Cotton_A_35104_BGI-A2_v1.0bHLH family protein
Cotton_A_35670_BGI-A2_v1.0bHLH family protein
Cotton_A_35715_BGI-A2_v1.0bHLH family protein
Cotton_A_35957_BGI-A2_v1.0bHLH family protein
Cotton_A_35960_BGI-A2_v1.0bHLH family protein
Cotton_A_36436_BGI-A2_v1.0bHLH family protein
Cotton_A_36525_BGI-A2_v1.0bHLH family protein
Cotton_A_36552_BGI-A2_v1.0bHLH family protein
Cotton_A_36794_BGI-A2_v1.0bHLH family protein
Cotton_A_36849_BGI-A2_v1.0bHLH family protein
Cotton_A_37193_BGI-A2_v1.0bHLH family protein
Cotton_A_37278_BGI-A2_v1.0bHLH family protein
Cotton_A_37465_BGI-A2_v1.0bHLH family protein
Cotton_A_37514_BGI-A2_v1.0bHLH family protein
Cotton_A_37582_BGI-A2_v1.0bHLH family protein
Cotton_A_38617_BGI-A2_v1.0bHLH family protein
Cotton_A_38636_BGI-A2_v1.0bHLH family protein
Cotton_A_38874_BGI-A2_v1.0bHLH family protein
Cotton_A_39383_BGI-A2_v1.0bHLH family protein
Cotton_A_39529_BGI-A2_v1.0bHLH family protein
Cotton_A_39797_BGI-A2_v1.0bHLH family protein
Cotton_A_39830_BGI-A2_v1.0bHLH family protein
Cotton_A_40026_BGI-A2_v1.0bHLH family protein
Cotton_A_40087_BGI-A2_v1.0bHLH family protein
Cotton_A_40771_BGI-A2_v1.0bHLH family protein
Cotton_A_41030_BGI-A2_v1.0bHLH family protein
bHLH Family Introduction

The basic/helix-loop-helix (bHLH) proteins are a superfamily of transcription factors that have been well characterized in nonplant eukaryotes, especially in mammalian systems, in which considerable structural, functional, and phylogenetic analyses have been performed. The data indicate that bHLH proteins are important regulatory components in transcriptional networks in these systems, controlling a diversity of processes from cell proliferation to cell lineage establishment.

This family is defined by the bHLH signature domain, which consists of 60 amino acids with two functionally distinct regions. The basic region, located at the N-terminal end of the domain, is involved in DNA binding and consists of 15 amino acids with a high number of basic residues. The HLH region, at the C-terminal end, functions as a dimerization domain and is constituted mainly of hydrophobic residues that form two amphipathic -helices separated by a loop region of variable sequence and length. Outside of the conserved bHLH domain, these proteins exhibit considerable sequence divergence. Cocrystal structural analysis has shown that the interaction between the HLH regions of two separate polypeptides leads to the formation of homodimers and/or heterodimers and that the basic region of each partner binds to half of the DNA recognition sequence. Some bHLH proteins form homodimers or restrict their heterodimerization activity to closely related members of the family. On the other hand, some can form heterodimers with one or several different partners.

The core DNA sequence motif recognized by the bHLH proteins is a consensus hexanucleotide sequence known as the E-box (5'-CANNTG-3'). There are different types of E-boxes, depending on the identity of the two central bases. One of the most common is the palindromic G-box (5'-CACGTG-3'). Certain conserved amino acids within the basic region of the protein provide recognition of the core consensus site, whereas other residues in the domain dictate specificity for a given type of E-box . In addition, flanking nucleotides outside of the hexanucleotide core have been shown to play a role in binding specificity, and there is evidence that a loop residue in the protein plays a role in DNA binding through elements that lie outside of the core recognition sequence.

Toledo-Ortiz G, Huq E, Quail PH.
The Arabidopsis basic/helix-loop-helix transcription factor family.
Plant Cell. 2003 Aug;15(8):1749-70
PMID: 12897250