PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Gossypium arboreum
WOX Family
Species TF ID Description
Cotton_A_02211_BGI-A2_v1.0WOX family protein
Cotton_A_40228_BGI-A2_v1.0WOX family protein
Cotton_A_08673_BGI-A2_v1.0WOX family protein
Cotton_A_01436_BGI-A2_v1.0WOX family protein
Cotton_A_01437_BGI-A2_v1.0WOX family protein
Cotton_A_10549_BGI-A2_v1.0WOX family protein
Cotton_A_22129_BGI-A2_v1.0WOX family protein
Cotton_A_07016_BGI-A2_v1.0WOX family protein
Cotton_A_11370_BGI-A2_v1.0WOX family protein
Cotton_A_31330_BGI-A2_v1.0WOX family protein
Cotton_A_11308_BGI-A2_v1.0WOX family protein
Cotton_A_03937_BGI-A2_v1.0WOX family protein
Cotton_A_22352_BGI-A2_v1.0WOX family protein
Cotton_A_39066_BGI-A2_v1.0WOX family protein
Cotton_A_24179_BGI-A2_v1.0WOX family protein
Cotton_A_34527_BGI-A2_v1.0WOX family protein
Cotton_A_05511_BGI-A2_v1.0WOX family protein
Cotton_A_17618_BGI-A2_v1.0WOX family protein
Cotton_A_28656_BGI-A2_v1.0WOX family protein
WOX Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401


The WOX genes form a plant-specific subclade of the eukaryotic homeobox transcription factor superfamily, which is characterized by the presence of a conserved DNA-binding homeodomain. The analysis of WOX gene expression and function shows that WOX family members fulfill specialized functions in key developmental processes in plants, such as embryonic patterning, stem-cell maintenance and organ formation. These functions can be related to either promotion of cell division activity and/or prevention of premature cell differentiation.

van der Graaff E, Laux T, Rensing SA.
The WUS homeobox-containing (WOX) protein family.
Genome Biol, 2009. 10(12): p. 248.
PMID: 20067590