PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Gossypium arboreum
NF-YA Family
Species TF ID Description
Cotton_A_02277_BGI-A2_v1.0NF-YA family protein
Cotton_A_02567_BGI-A2_v1.0NF-YA family protein
Cotton_A_02671_BGI-A2_v1.0NF-YA family protein
Cotton_A_03153_BGI-A2_v1.0NF-YA family protein
Cotton_A_03321_BGI-A2_v1.0NF-YA family protein
Cotton_A_05707_BGI-A2_v1.0NF-YA family protein
Cotton_A_06049_BGI-A2_v1.0NF-YA family protein
Cotton_A_06685_BGI-A2_v1.0NF-YA family protein
Cotton_A_08538_BGI-A2_v1.0NF-YA family protein
Cotton_A_10241_BGI-A2_v1.0NF-YA family protein
Cotton_A_12983_BGI-A2_v1.0NF-YA family protein
Cotton_A_16018_BGI-A2_v1.0NF-YA family protein
Cotton_A_24712_BGI-A2_v1.0NF-YA family protein
Cotton_A_26079_BGI-A2_v1.0NF-YA family protein
Cotton_A_29133_BGI-A2_v1.0NF-YA family protein
Cotton_A_36618_BGI-A2_v1.0NF-YA family protein
Cotton_A_39954_BGI-A2_v1.0NF-YA family protein
NF-YA Family Introduction

NF-Y transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NF-Y transcription factor complex is composed of three unique subunits: NF-YA, NF-YB, and NF-YC. Assembly of the NF-Y heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NF-YB and NF-YC. This dimer then translocates to the nucleus, where the third subunit, NF-YA, is recruited to generate the mature, heterotrimeric NF-Y transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NF-Y binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).

NF-YA proteins are characterized by the presence of Gln(Q)- and Ser/Thr(S/T)-rich NH2 termini, a subunit interaction domain (NF-YB/NF-YC interaction), and a DNA-binding domain (Olesen and Guarente, 1990; Maity and de Crombrugghe, 1992; Xing et al., 1993, 1994). The protein interaction and DNA binding domains are well conserved between plant and other eukaryote lineages.

Siefers N, Dang KK, Kumimoto RW, Bynum WE 4th, Tayrose G, Holt BF 3rd.
Tissue-specific expression patterns of Arabidopsis NF-Y transcription factors suggest potential for extensive combinatorial complexity.
Plant Physiol, 2009. 149(2): p. 625-41.
PMID: 19019982