PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Gossypium arboreum
HSF Family
Species TF ID Description
Cotton_A_00864_BGI-A2_v1.0HSF family protein
Cotton_A_01784_BGI-A2_v1.0HSF family protein
Cotton_A_02851_BGI-A2_v1.0HSF family protein
Cotton_A_03896_BGI-A2_v1.0HSF family protein
Cotton_A_05313_BGI-A2_v1.0HSF family protein
Cotton_A_05720_BGI-A2_v1.0HSF family protein
Cotton_A_05732_BGI-A2_v1.0HSF family protein
Cotton_A_07392_BGI-A2_v1.0HSF family protein
Cotton_A_07539_BGI-A2_v1.0HSF family protein
Cotton_A_07921_BGI-A2_v1.0HSF family protein
Cotton_A_08195_BGI-A2_v1.0HSF family protein
Cotton_A_08661_BGI-A2_v1.0HSF family protein
Cotton_A_09028_BGI-A2_v1.0HSF family protein
Cotton_A_09182_BGI-A2_v1.0HSF family protein
Cotton_A_09236_BGI-A2_v1.0HSF family protein
Cotton_A_09357_BGI-A2_v1.0HSF family protein
Cotton_A_09986_BGI-A2_v1.0HSF family protein
Cotton_A_11156_BGI-A2_v1.0HSF family protein
Cotton_A_11627_BGI-A2_v1.0HSF family protein
Cotton_A_13446_BGI-A2_v1.0HSF family protein
Cotton_A_14508_BGI-A2_v1.0HSF family protein
Cotton_A_14557_BGI-A2_v1.0HSF family protein
Cotton_A_14899_BGI-A2_v1.0HSF family protein
Cotton_A_16493_BGI-A2_v1.0HSF family protein
Cotton_A_16993_BGI-A2_v1.0HSF family protein
Cotton_A_17577_BGI-A2_v1.0HSF family protein
Cotton_A_17661_BGI-A2_v1.0HSF family protein
Cotton_A_22025_BGI-A2_v1.0HSF family protein
Cotton_A_23520_BGI-A2_v1.0HSF family protein
Cotton_A_24993_BGI-A2_v1.0HSF family protein
Cotton_A_25297_BGI-A2_v1.0HSF family protein
Cotton_A_25561_BGI-A2_v1.0HSF family protein
Cotton_A_30136_BGI-A2_v1.0HSF family protein
Cotton_A_33085_BGI-A2_v1.0HSF family protein
Cotton_A_33386_BGI-A2_v1.0HSF family protein
Cotton_A_34171_BGI-A2_v1.0HSF family protein
Cotton_A_37093_BGI-A2_v1.0HSF family protein
Cotton_A_37622_BGI-A2_v1.0HSF family protein
Cotton_A_37899_BGI-A2_v1.0HSF family protein
Cotton_A_38701_BGI-A2_v1.0HSF family protein
Cotton_A_39878_BGI-A2_v1.0HSF family protein
HSF Family Introduction

Heat stress transcription factors (Hsfs) are the major regulators of the plant heat stress (hs) response. Sequencing of the Arabidopsis genome revealed the existence of 21 open-reading frames (ORFs) encoding putative Hsfs assigned to classes A-C. Here we present results of a functional genomics approach to the Arabidopsis Hsf family focused on the analysis of their C-terminal domains (CTDs) harboring conserved modules for their function as transcription factors and their intracellular localization. Using reporter assays in tobacco protoplasts and yeast as well as glutathione-S-transferase (GST) pull-down assays, we demonstrate that short peptide motifs enriched with aromatic and large hydrophobic amino acid (aa) residues embedded in an acidic surrounding (AHA motifs) are essential for transcriptional activity of class A Hsfs. In contrast to this, class B and C Hsfs lack AHA motifs and have no activator function on their own. We also provide evidence for the function of a leucine (Leu)-rich region centered around a conserved QMGΦL motif at the very C-terminus as a nuclear export signal (NES) of class A Hsfs. Sequence comparison indicates that the combination of a C-terminal AHA motif with the consensus sequence FWxxF/L,F/I/L as well as the adjacent NES represents a signature domain for plant class A Hsfs, which allowed to identify more than 60 new Hsfs from the expressed sequence tag (EST) database.

Kotak S, Port M, Ganguli A, Bicker F, von Koskull-Doring P.
Characterization of C-terminal domains of Arabidopsis heat stress transcription factors (Hsfs) and identification of a new signature combination of plant class A Hsfs with AHA and NES motifs essential for activator function and intracellular localization.
Plant J, 2004. 39(1): p. 98-112.
PMID: 15200645