PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Gossypium arboreum
HD-ZIP Family
Species TF ID Description
Cotton_A_16168_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_38457_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_26317_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_27957_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_11191_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_30333_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_09138_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_07152_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_15440_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_27084_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_24633_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_25802_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_06354_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_02692_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_22902_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_26519_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_07682_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_20373_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_09802_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_24777_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_02815_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_29012_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_07684_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_31305_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_31306_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_37018_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_07685_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_10835_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_39533_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_19429_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_41261_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_19290_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_00507_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_17302_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_25888_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_00505_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_27816_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_27817_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_35320_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_02375_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_34158_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_01632_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_37086_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_32300_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_30465_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_02021_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_13207_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_32808_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_06253_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_34913_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_21639_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_05379_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_35739_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_01049_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_38379_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_32341_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_25654_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_40124_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_24123_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_03394_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_20473_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_05396_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_01469_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_22259_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_10243_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_32389_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_38798_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_05129_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_07197_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_07061_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_10520_BGI-A2_v1.0HD-ZIP family protein
Cotton_A_04266_BGI-A2_v1.0HD-ZIP family protein
HD-ZIP Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Members of the HD-Zip family have a leucine zipper motif (LZ) immediately downstream of the HD. The two motifs are present in transcription factors found in species belonging to other eukaryotic kingdoms, but their association in a single protein is unique to plants. The HD is responsible for the specific binding to DNA, whereas LZ acts as a dimerization motif. HD-Zip proteins bind to DNA as dimers, and the absence of LZ absolutely abolishes their binding ability, which indicates that the relative orientation of the monomers, driven by this motif, is crucial for an efficient recognition of DNA.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401