PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Fragaria vesca
FAR1 Family
Species TF ID Description
mrna00378.1-v1.0-hybridFAR1 family protein
mrna01536.1-v1.0-hybridFAR1 family protein
mrna02297.1-v1.0-hybridFAR1 family protein
mrna03360.1-v1.0-hybridFAR1 family protein
mrna03384.1-v1.0-hybridFAR1 family protein
mrna05172.1-v1.0-hybridFAR1 family protein
mrna06133.1-v1.0-hybridFAR1 family protein
mrna06165.1-v1.0-hybridFAR1 family protein
mrna08567.1-v1.0-hybridFAR1 family protein
mrna10034.1-v1.0-hybridFAR1 family protein
mrna10669.1-v1.0-hybridFAR1 family protein
mrna10972.1-v1.0-hybridFAR1 family protein
mrna11523.1-v1.0-hybridFAR1 family protein
mrna11611.1-v1.0-hybridFAR1 family protein
mrna11645.1-v1.0-hybridFAR1 family protein
mrna12330.1-v1.0-hybridFAR1 family protein
mrna12562.1-v1.0-hybridFAR1 family protein
mrna12906.1-v1.0-hybridFAR1 family protein
mrna12968.1-v1.0-hybridFAR1 family protein
mrna12983.1-v1.0-hybridFAR1 family protein
mrna13309.1-v1.0-hybridFAR1 family protein
mrna14142.1-v1.0-hybridFAR1 family protein
mrna14237.1-v1.0-hybridFAR1 family protein
mrna14932.1-v1.0-hybridFAR1 family protein
mrna15264.1-v1.0-hybridFAR1 family protein
mrna15606.1-v1.0-hybridFAR1 family protein
mrna15609.1-v1.0-hybridFAR1 family protein
mrna15714.1-v1.0-hybridFAR1 family protein
mrna15716.1-v1.0-hybridFAR1 family protein
mrna16000.1-v1.0-hybridFAR1 family protein
mrna16188.1-v1.0-hybridFAR1 family protein
mrna16389.1-v1.0-hybridFAR1 family protein
mrna17030.1-v1.0-hybridFAR1 family protein
mrna17117.1-v1.0-hybridFAR1 family protein
mrna17500.1-v1.0-hybridFAR1 family protein
mrna17501.1-v1.0-hybridFAR1 family protein
mrna18002.1-v1.0-hybridFAR1 family protein
mrna18743.1-v1.0-hybridFAR1 family protein
mrna19368.1-v1.0-hybridFAR1 family protein
mrna19817.1-v1.0-hybridFAR1 family protein
mrna19997.1-v1.0-hybridFAR1 family protein
mrna20579.1-v1.0-hybridFAR1 family protein
mrna21527.1-v1.0-hybridFAR1 family protein
mrna21528.1-v1.0-hybridFAR1 family protein
mrna21668.1-v1.0-hybridFAR1 family protein
mrna21669.1-v1.0-hybridFAR1 family protein
mrna21819.1-v1.0-hybridFAR1 family protein
mrna23260.1-v1.0-hybridFAR1 family protein
mrna23545.1-v1.0-hybridFAR1 family protein
mrna23639.1-v1.0-hybridFAR1 family protein
mrna24047.1-v1.0-hybridFAR1 family protein
mrna24214.1-v1.0-hybridFAR1 family protein
mrna24215.1-v1.0-hybridFAR1 family protein
mrna24216.1-v1.0-hybridFAR1 family protein
mrna24375.1-v1.0-hybridFAR1 family protein
mrna24916.1-v1.0-hybridFAR1 family protein
mrna25522.1-v1.0-hybridFAR1 family protein
mrna28610.1-v1.0-hybridFAR1 family protein
mrna28724.1-v1.0-hybridFAR1 family protein
mrna28846.1-v1.0-hybridFAR1 family protein
mrna29088.1-v1.0-hybridFAR1 family protein
mrna29166.1-v1.0-hybridFAR1 family protein
mrna29863.1-v1.0-hybridFAR1 family protein
mrna30107.1-v1.0-hybridFAR1 family protein
mrna31211.1-v1.0-hybridFAR1 family protein
mrna31920.1-v1.0-hybridFAR1 family protein
mrna32690.1-v1.0-hybridFAR1 family protein
mrna34104.1-v1.0-hybridFAR1 family protein
mrna34139.1-v1.0-hybridFAR1 family protein
mrna34213.1-v1.0-hybridFAR1 family protein
mrna34277.1-v1.0-hybridFAR1 family protein
mrna34500.1-v1.0-hybridFAR1 family protein
mrna34568.1-v1.0-hybridFAR1 family protein
mrna34612.1-v1.0-hybridFAR1 family protein
mrna34674.1-v1.0-hybridFAR1 family protein
mrna34707.1-v1.0-hybridFAR1 family protein
mrna34728.1-v1.0-hybridFAR1 family protein
mrna34923.1-v1.0-hybridFAR1 family protein
mrna34935.1-v1.0-hybridFAR1 family protein
mrna35102.1-v1.0-hybridFAR1 family protein
mrna35121.1-v1.0-hybridFAR1 family protein
mrna35144.1-v1.0-hybridFAR1 family protein
FAR1 Family Introduction

We show that Arabidopsis FHY3 and FAR1, which encode two proteins related to Mutator-like transposases, act together to modulate phyA signaling by directly activating the transcription of FHY1 and FHL, whose products are essential for light-induced phyA nuclear accumulation and subsequent light responses. FHY3 and FAR1 have separable DNA binding and transcriptional activation domains that are highly conserved in Mutator-like transposases. Further, expression of FHY3 and FAR1 is negatively regulated by phyA signaling. We propose that FHY3 and FAR1 represent transcription factors that have been co-opted from an ancient Mutator-like transposase(s) to modulate phyA-signaling homeostasis in higher plants.

We next used a yeast one-hybrid assay to delineate the DNA sequences to which FHY3 and FAR1 bind. GAD-FHY3 or GAD-FAR1 fusion proteins (GAD, GAL4 transcriptional activation domain), but not GAD alone, activated the LacZ reporter genes driven by the FHY1 and FHL promoters. Deletion analysis narrowed down the FHY3/FAR1 binding site to a 39-bp promoter subfragment located on the "a" fragment for both FHY1 and FHL. Notably, these subfragments share a stretch of consensus sequence, 5'-TTCACGCGCC-3'. Mutating the core sequence "CACGCGC" of this motif (m2 and m3 for FHY1, m5 for FHL) abolished the reporter gene activation by both GAD-FHY3 and GAD-FAR1. Mutating the flanking sequences (m1 and m4) did not obviously affect the reporter gene activation by GAD-FAR1, but clearly reduced activation by GAD-FHY3. Thus, "CACGCGC" likely defines a cis-element that confers specific binding for FHY3 and FAR1 and is named FBS for FHY3-FAR1 binding site.

Lin R, Ding L, Casola C, Ripoll DR, Feschotte C, Wang H.
Transposase-derived transcription factors regulate light signaling in Arabidopsis.
Science, 2007. 318(5854): p. 1302-5.
PMID: 18033885