PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Eragrostis tef
WRKY Family
Species TF ID Description
462845408WRKY family protein
462845562WRKY family protein
462845728WRKY family protein
462847106WRKY family protein
462848225WRKY family protein
462849770WRKY family protein
462850189WRKY family protein
462850210WRKY family protein
462850264WRKY family protein
462850279WRKY family protein
462850306WRKY family protein
462850964WRKY family protein
462850966WRKY family protein
462851070WRKY family protein
462851278WRKY family protein
462851434WRKY family protein
462855928WRKY family protein
462858153WRKY family protein
462858734WRKY family protein
462858982WRKY family protein
462861057WRKY family protein
462861451WRKY family protein
462861454WRKY family protein
462862919WRKY family protein
462863258WRKY family protein
462863949WRKY family protein
462864828WRKY family protein
462867132WRKY family protein
462868354WRKY family protein
462869308WRKY family protein
462869334WRKY family protein
462869469WRKY family protein
462873377WRKY family protein
462873952WRKY family protein
462875262WRKY family protein
462875853WRKY family protein
462877143WRKY family protein
462879680WRKY family protein
462881564WRKY family protein
462882673WRKY family protein
462884741WRKY family protein
462884744WRKY family protein
462885943WRKY family protein
462889020WRKY family protein
462890926WRKY family protein
462891797WRKY family protein
462892791WRKY family protein
462893124WRKY family protein
462893136WRKY family protein
462893379WRKY family protein
462893394WRKY family protein
462894431WRKY family protein
462895139WRKY family protein
462895467WRKY family protein
462897697WRKY family protein
462899991WRKY family protein
462900060WRKY family protein
462902897WRKY family protein
462903065WRKY family protein
462903067WRKY family protein
462904627WRKY family protein
462907069WRKY family protein
462907072WRKY family protein
462907093WRKY family protein
462907195WRKY family protein
462907198WRKY family protein
462907201WRKY family protein
462907897WRKY family protein
462909549WRKY family protein
462911823WRKY family protein
462912040WRKY family protein
462912290WRKY family protein
462915712WRKY family protein
462916456WRKY family protein
462916519WRKY family protein
462917573WRKY family protein
462919113WRKY family protein
462919713WRKY family protein
462920550WRKY family protein
462920863WRKY family protein
462923133WRKY family protein
462923136WRKY family protein
462923139WRKY family protein
462923647WRKY family protein
462925359WRKY family protein
462929181WRKY family protein
462931217WRKY family protein
462931673WRKY family protein
462933107WRKY family protein
462935944WRKY family protein
462936503WRKY family protein
462937180WRKY family protein
462937858WRKY family protein
462938704WRKY family protein
462939384WRKY family protein
462940225WRKY family protein
462940369WRKY family protein
462940372WRKY family protein
462943699WRKY family protein
462945927WRKY family protein
462945929WRKY family protein
462946594WRKY family protein
462948041WRKY family protein
462950116WRKY family protein
462950509WRKY family protein
462952672WRKY family protein
462952675WRKY family protein
462955285WRKY family protein
462955458WRKY family protein
462955526WRKY family protein
462955651WRKY family protein
462956461WRKY family protein
462958166WRKY family protein
462958522WRKY family protein
462961015WRKY family protein
462961192WRKY family protein
462963808WRKY family protein
462965737WRKY family protein
462969508WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701