PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Eragrostis tef
ARF Family
Species TF ID Description
462860392ARF family protein
462860570ARF family protein
462860572ARF family protein
462863710ARF family protein
462865345ARF family protein
462868638ARF family protein
462869223ARF family protein
462875585ARF family protein
462875587ARF family protein
462880182ARF family protein
462880794ARF family protein
462882127ARF family protein
462885283ARF family protein
462885723ARF family protein
462886934ARF family protein
462888637ARF family protein
462896072ARF family protein
462907353ARF family protein
462913466ARF family protein
462914517ARF family protein
462916198ARF family protein
462917549ARF family protein
462918339ARF family protein
462919167ARF family protein
462926535ARF family protein
462926628ARF family protein
462930158ARF family protein
462931853ARF family protein
462940970ARF family protein
462947062ARF family protein
462949451ARF family protein
462950574ARF family protein
462954133ARF family protein
462956348ARF family protein
462958011ARF family protein
462958810ARF family protein
462958812ARF family protein
462960632ARF family protein
462960634ARF family protein
462963347ARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969