PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Elaeis guineensis
MIKC_MADS Family
Species TF ID Description
XP_010905324.1MIKC_MADS family protein
XP_010906391.1MIKC_MADS family protein
XP_010908080.1MIKC_MADS family protein
XP_010909781.1MIKC_MADS family protein
XP_010911080.1MIKC_MADS family protein
XP_010911265.1MIKC_MADS family protein
XP_010911271.1MIKC_MADS family protein
XP_010912706.1MIKC_MADS family protein
XP_010912707.1MIKC_MADS family protein
XP_010912876.1MIKC_MADS family protein
XP_010913017.1MIKC_MADS family protein
XP_010913018.1MIKC_MADS family protein
XP_010914210.1MIKC_MADS family protein
XP_010914211.1MIKC_MADS family protein
XP_010914212.1MIKC_MADS family protein
XP_010914213.1MIKC_MADS family protein
XP_010914214.1MIKC_MADS family protein
XP_010914215.1MIKC_MADS family protein
XP_010915440.1MIKC_MADS family protein
XP_010915441.1MIKC_MADS family protein
XP_010915442.1MIKC_MADS family protein
XP_010915443.1MIKC_MADS family protein
XP_010915444.1MIKC_MADS family protein
XP_010915445.1MIKC_MADS family protein
XP_010915446.1MIKC_MADS family protein
XP_010916111.1MIKC_MADS family protein
XP_010916144.1MIKC_MADS family protein
XP_010917558.1MIKC_MADS family protein
XP_010917559.1MIKC_MADS family protein
XP_010917560.1MIKC_MADS family protein
XP_010919080.1MIKC_MADS family protein
XP_010919081.1MIKC_MADS family protein
XP_010919082.1MIKC_MADS family protein
XP_010923638.1MIKC_MADS family protein
XP_010925573.1MIKC_MADS family protein
XP_010926159.1MIKC_MADS family protein
XP_010926160.1MIKC_MADS family protein
XP_010926365.1MIKC_MADS family protein
XP_010926366.1MIKC_MADS family protein
XP_010926838.1MIKC_MADS family protein
XP_010926839.1MIKC_MADS family protein
XP_010927866.1MIKC_MADS family protein
XP_010930410.1MIKC_MADS family protein
XP_010930411.1MIKC_MADS family protein
XP_010930412.1MIKC_MADS family protein
XP_010932626.1MIKC_MADS family protein
XP_010934005.1MIKC_MADS family protein
XP_010934006.1MIKC_MADS family protein
XP_010934007.1MIKC_MADS family protein
XP_010934008.1MIKC_MADS family protein
XP_010934009.1MIKC_MADS family protein
XP_010934010.1MIKC_MADS family protein
XP_010934012.1MIKC_MADS family protein
XP_010934013.1MIKC_MADS family protein
XP_010934917.1MIKC_MADS family protein
XP_010934918.1MIKC_MADS family protein
XP_010934919.1MIKC_MADS family protein
XP_010934920.1MIKC_MADS family protein
XP_010934921.1MIKC_MADS family protein
XP_010934922.1MIKC_MADS family protein
XP_010934923.1MIKC_MADS family protein
XP_010934925.1MIKC_MADS family protein
XP_010936436.1MIKC_MADS family protein
XP_010936437.1MIKC_MADS family protein
XP_010936438.1MIKC_MADS family protein
XP_010937970.1MIKC_MADS family protein
XP_010937979.1MIKC_MADS family protein
XP_010937987.1MIKC_MADS family protein
XP_010937995.1MIKC_MADS family protein
XP_010938015.1MIKC_MADS family protein
XP_010939217.1MIKC_MADS family protein
XP_010939774.1MIKC_MADS family protein
XP_010941167.1MIKC_MADS family protein
XP_010941168.1MIKC_MADS family protein
XP_010941169.1MIKC_MADS family protein
XP_010941170.1MIKC_MADS family protein
XP_010941171.1MIKC_MADS family protein
XP_010942683.1MIKC_MADS family protein
XP_010942684.1MIKC_MADS family protein
MIKC_MADS (MIKC-type MADS) Family Introduction

The best studied plant MADS-box transcription factors are those involved in floral organ identity determination. Analysis of homeotic floral mutants resulted in the formulation of a genetic model, named the ABC model, that explains how the combined functions of three classes of genes (A, B, and C) determine the identity of the four flower organs (reviewed by Coen and Meyerowitz, 1991). Arabidopsis has two A-class genes (AP1 and AP2 [Bowman et al., 1989]), two B-class genes (PI and AP3), and a single C-class gene (AG), of which only AP2 is not a MADS-box gene. Recently, it was shown that the Arabidopsis B- and C-function genes, which control petal, stamen, and carpel development, are functionally dependent on three highly similar MADS-box genes, SEP1, SEP2, and SEP3 (Pelaz et al., 2000). Interestingly, only when mutant knockout alleles of the three SEP genes were combined in a triple sep1 sep2 sep3 mutant was loss of petal, stamen, and carpel identity observed, resulting in a flower composed of only sepals. This example shows that redundancy occurs in the MADS-box gene family, which complicates reverse genetic strategies for gene function analysis. The SHP genes provide another example of MADS-box gene redundancy. shp1 and shp2 single mutants do not exhibit any phenotypic effect, whereas in the double mutant, development of the dehiscence zone is disturbed in the fruit, resulting in a failure to release seeds (Liljegren et al., 2000)[1].

It has been proposed that there are at least 2 lineages (type I and type II) of MADS-box genes in plants, animals, and fungi. Most of the well-studied plant genes are type II genes and have three more domains than type I genes from the N to the C terminus of the protein:intervening (I) domain (~30 codons), keratin-lik e coiled-coil (K) domain (~70 codons), and Cterminal (C) domain (variable length). These genes are called the MIKC-type and are specific to plants[2].

The MADS-box is a DNA binding domain of 58 amino acids that binds DNA at consensus recognition sequences known as CArG boxes [CC(A/T)6GG] (Hayes et al., 1988; Riechmann et al., 1996b). The interaction with DNA has been studied in detail for the human and yeast MADS-box proteins thanks to the resolved crystal structures (Pellegrini et al., 1995; Santelli and Richmond, 2000). The I domain is less conserved and contributes to the specification of dimerization. The K domain is characterized by a coiled-coil structure, which facilitates the dimerization of MADS-box proteins (Davies et al., 1996; Fan et al., 1997). The C domain is the least conserved domain; in some cases, it has been shown to contain a transactivation domain or to contribute to the formation of multimeric MADS-box protein complexes (Egea-Cortines et al., 1999; Honma and Goto, 2001)[1].

1.Parenicova L, de Folter S, Kieffer M, Horner DS, Favalli C, Busscher J, Cook HE, Ingram RM, Kater MM, Davies B, Angenent GC, Colombo L.
Molecular and phylogenetic analyses of the complete MADS-box transcription factor family in Arabidopsis: new openings to the MADS world.
Plant Cell. 2003 Jul;15(7):1538-51.
PMID: 12837945
2.Nam J, dePamphilis CW, Ma H, Nei M.
Antiquity and evolution of the MADS-box gene family controlling flower development in plants.
Mol Biol Evol. 2003 Sep;20(9):1435-47. Epub 2003 May 30.
PMID: 12777513