PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Elaeis guineensis
HD-ZIP Family
Species TF ID Description
XP_010928608.1HD-ZIP family protein
XP_010913582.1HD-ZIP family protein
XP_010915101.1HD-ZIP family protein
XP_010928609.1HD-ZIP family protein
XP_010942613.1HD-ZIP family protein
XP_010917010.1HD-ZIP family protein
XP_010925357.1HD-ZIP family protein
XP_010931687.1HD-ZIP family protein
XP_010939701.1HD-ZIP family protein
XP_010939547.1HD-ZIP family protein
XP_010926222.1HD-ZIP family protein
XP_010937067.1HD-ZIP family protein
XP_010933626.1HD-ZIP family protein
XP_010926338.1HD-ZIP family protein
XP_010919661.1HD-ZIP family protein
XP_010917267.1HD-ZIP family protein
XP_010934651.1HD-ZIP family protein
XP_010916708.1HD-ZIP family protein
XP_010936202.1HD-ZIP family protein
XP_010941065.1HD-ZIP family protein
XP_010939328.1HD-ZIP family protein
XP_010924194.1HD-ZIP family protein
XP_010925064.1HD-ZIP family protein
XP_010924919.1HD-ZIP family protein
XP_010919351.1HD-ZIP family protein
XP_010933776.1HD-ZIP family protein
XP_010925063.1HD-ZIP family protein
XP_010943413.1HD-ZIP family protein
XP_010920063.1HD-ZIP family protein
XP_010905085.1HD-ZIP family protein
XP_010941970.1HD-ZIP family protein
XP_010913846.1HD-ZIP family protein
XP_010943164.1HD-ZIP family protein
XP_010928969.1HD-ZIP family protein
XP_010933377.1HD-ZIP family protein
XP_010933376.1HD-ZIP family protein
XP_010927053.1HD-ZIP family protein
XP_010936817.1HD-ZIP family protein
XP_010936816.1HD-ZIP family protein
XP_010936829.1HD-ZIP family protein
XP_010905884.1HD-ZIP family protein
XP_010931820.1HD-ZIP family protein
XP_010931821.1HD-ZIP family protein
XP_010908855.1HD-ZIP family protein
XP_010920420.1HD-ZIP family protein
XP_010920411.1HD-ZIP family protein
XP_010920404.1HD-ZIP family protein
XP_010919252.1HD-ZIP family protein
XP_010919251.1HD-ZIP family protein
XP_010919250.1HD-ZIP family protein
XP_010933869.1HD-ZIP family protein
XP_010915412.1HD-ZIP family protein
XP_010915411.1HD-ZIP family protein
XP_010915409.1HD-ZIP family protein
XP_010915410.1HD-ZIP family protein
XP_010917295.1HD-ZIP family protein
XP_010939971.1HD-ZIP family protein
XP_010932508.1HD-ZIP family protein
XP_010934555.1HD-ZIP family protein
XP_010905421.1HD-ZIP family protein
XP_010905420.1HD-ZIP family protein
XP_010923678.1HD-ZIP family protein
XP_010936845.1HD-ZIP family protein
XP_010936847.1HD-ZIP family protein
XP_010920423.1HD-ZIP family protein
XP_010920424.1HD-ZIP family protein
XP_010920418.1HD-ZIP family protein
XP_010920419.1HD-ZIP family protein
XP_010920421.1HD-ZIP family protein
XP_010930674.1HD-ZIP family protein
XP_010933428.1HD-ZIP family protein
XP_010931877.1HD-ZIP family protein
XP_010919976.1HD-ZIP family protein
XP_010920422.1HD-ZIP family protein
HD-ZIP Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Members of the HD-Zip family have a leucine zipper motif (LZ) immediately downstream of the HD. The two motifs are present in transcription factors found in species belonging to other eukaryotic kingdoms, but their association in a single protein is unique to plants. The HD is responsible for the specific binding to DNA, whereas LZ acts as a dimerization motif. HD-Zip proteins bind to DNA as dimers, and the absence of LZ absolutely abolishes their binding ability, which indicates that the relative orientation of the monomers, driven by this motif, is crucial for an efficient recognition of DNA.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401