PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Dianthus caryophyllus
WRKY Family
Species TF ID Description
Dca14116.1WRKY family protein
Dca14210.1WRKY family protein
Dca16797.1WRKY family protein
Dca16932.1WRKY family protein
Dca19236.1WRKY family protein
Dca19563.1WRKY family protein
Dca20179.1WRKY family protein
Dca20613.1WRKY family protein
Dca22042.1WRKY family protein
Dca23260.1WRKY family protein
Dca23485.1WRKY family protein
Dca244.1WRKY family protein
Dca25171.1WRKY family protein
Dca26741.1WRKY family protein
Dca29997.1WRKY family protein
Dca30201.1WRKY family protein
Dca30498.1WRKY family protein
Dca31222.1WRKY family protein
Dca31336.1WRKY family protein
Dca31681.1WRKY family protein
Dca31911.1WRKY family protein
Dca33501.1WRKY family protein
Dca34429.1WRKY family protein
Dca35085.1WRKY family protein
Dca35676.1WRKY family protein
Dca36695.1WRKY family protein
Dca37091.1WRKY family protein
Dca37501.1WRKY family protein
Dca3904.1WRKY family protein
Dca39766.1WRKY family protein
Dca41468.1WRKY family protein
Dca42244.1WRKY family protein
Dca42273.1WRKY family protein
Dca4257.1WRKY family protein
Dca44848.1WRKY family protein
Dca46559.1WRKY family protein
Dca48297.1WRKY family protein
Dca49884.1WRKY family protein
Dca50783.1WRKY family protein
Dca50831.1WRKY family protein
Dca50999.1WRKY family protein
Dca51966.1WRKY family protein
Dca52455.1WRKY family protein
Dca54455.1WRKY family protein
Dca55933.1WRKY family protein
Dca57560.1WRKY family protein
Dca58729.1WRKY family protein
Dca5929.1WRKY family protein
Dca59343.1WRKY family protein
Dca59973.1WRKY family protein
Dca60139.1WRKY family protein
Dca61266.1WRKY family protein
Dca7696.1WRKY family protein
Dca7723.1WRKY family protein
Dca8577.1WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701