PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Dianthus caryophyllus
FAR1 Family
Species TF ID Description
Dca11075.1FAR1 family protein
Dca11514.1FAR1 family protein
Dca11741.1FAR1 family protein
Dca12014.1FAR1 family protein
Dca12897.1FAR1 family protein
Dca13804.1FAR1 family protein
Dca13893.1FAR1 family protein
Dca13909.1FAR1 family protein
Dca13941.1FAR1 family protein
Dca13949.1FAR1 family protein
Dca14026.1FAR1 family protein
Dca14273.1FAR1 family protein
Dca14717.1FAR1 family protein
Dca15166.1FAR1 family protein
Dca15636.1FAR1 family protein
Dca1591.1FAR1 family protein
Dca1665.1FAR1 family protein
Dca18404.1FAR1 family protein
Dca18790.1FAR1 family protein
Dca19321.1FAR1 family protein
Dca20074.1FAR1 family protein
Dca20462.1FAR1 family protein
Dca22243.1FAR1 family protein
Dca22247.1FAR1 family protein
Dca2228.1FAR1 family protein
Dca22366.1FAR1 family protein
Dca22638.1FAR1 family protein
Dca23866.1FAR1 family protein
Dca23924.1FAR1 family protein
Dca24376.1FAR1 family protein
Dca24506.1FAR1 family protein
Dca24575.1FAR1 family protein
Dca24879.1FAR1 family protein
Dca25431.1FAR1 family protein
Dca25555.1FAR1 family protein
Dca25750.1FAR1 family protein
Dca26323.1FAR1 family protein
Dca27034.1FAR1 family protein
Dca27707.1FAR1 family protein
Dca28821.1FAR1 family protein
Dca29676.1FAR1 family protein
Dca30125.1FAR1 family protein
Dca30741.1FAR1 family protein
Dca30837.1FAR1 family protein
Dca31014.1FAR1 family protein
Dca31157.1FAR1 family protein
Dca31467.1FAR1 family protein
Dca32215.1FAR1 family protein
Dca32496.1FAR1 family protein
Dca34946.1FAR1 family protein
Dca35233.1FAR1 family protein
Dca35561.1FAR1 family protein
Dca36594.1FAR1 family protein
Dca36694.1FAR1 family protein
Dca37232.1FAR1 family protein
Dca37828.1FAR1 family protein
Dca38163.1FAR1 family protein
Dca38493.1FAR1 family protein
Dca39468.1FAR1 family protein
Dca40280.1FAR1 family protein
Dca40382.1FAR1 family protein
Dca4047.1FAR1 family protein
Dca40839.1FAR1 family protein
Dca42192.1FAR1 family protein
Dca42208.1FAR1 family protein
Dca4226.1FAR1 family protein
Dca42492.1FAR1 family protein
Dca42659.1FAR1 family protein
Dca42706.1FAR1 family protein
Dca43462.1FAR1 family protein
Dca45418.1FAR1 family protein
Dca45434.1FAR1 family protein
Dca45672.1FAR1 family protein
Dca45873.1FAR1 family protein
Dca46065.1FAR1 family protein
Dca46157.1FAR1 family protein
Dca46464.1FAR1 family protein
Dca46507.1FAR1 family protein
Dca46628.1FAR1 family protein
Dca46740.1FAR1 family protein
Dca47347.1FAR1 family protein
Dca48048.1FAR1 family protein
Dca4867.1FAR1 family protein
Dca48741.1FAR1 family protein
Dca4893.1FAR1 family protein
Dca49401.1FAR1 family protein
Dca49465.1FAR1 family protein
Dca50560.1FAR1 family protein
Dca5065.1FAR1 family protein
Dca50747.1FAR1 family protein
Dca50986.1FAR1 family protein
Dca51244.1FAR1 family protein
Dca51338.1FAR1 family protein
Dca51471.1FAR1 family protein
Dca51488.1FAR1 family protein
Dca51501.1FAR1 family protein
Dca51545.1FAR1 family protein
Dca52376.1FAR1 family protein
Dca5248.1FAR1 family protein
Dca52726.1FAR1 family protein
Dca52922.1FAR1 family protein
Dca5358.1FAR1 family protein
Dca53658.1FAR1 family protein
Dca54358.1FAR1 family protein
Dca54524.1FAR1 family protein
Dca54711.1FAR1 family protein
Dca5515.1FAR1 family protein
Dca57086.1FAR1 family protein
Dca57295.1FAR1 family protein
Dca58095.1FAR1 family protein
Dca58361.1FAR1 family protein
Dca5850.1FAR1 family protein
Dca59067.1FAR1 family protein
Dca59489.1FAR1 family protein
Dca59571.1FAR1 family protein
Dca5971.1FAR1 family protein
Dca60105.1FAR1 family protein
Dca60208.1FAR1 family protein
Dca60720.1FAR1 family protein
Dca61222.1FAR1 family protein
Dca61559.1FAR1 family protein
Dca61632.1FAR1 family protein
Dca61967.1FAR1 family protein
Dca62504.1FAR1 family protein
Dca6453.1FAR1 family protein
Dca6677.1FAR1 family protein
Dca7640.1FAR1 family protein
Dca7705.1FAR1 family protein
Dca8764.1FAR1 family protein
Dca9008.1FAR1 family protein
Dca9174.1FAR1 family protein
FAR1 Family Introduction

We show that Arabidopsis FHY3 and FAR1, which encode two proteins related to Mutator-like transposases, act together to modulate phyA signaling by directly activating the transcription of FHY1 and FHL, whose products are essential for light-induced phyA nuclear accumulation and subsequent light responses. FHY3 and FAR1 have separable DNA binding and transcriptional activation domains that are highly conserved in Mutator-like transposases. Further, expression of FHY3 and FAR1 is negatively regulated by phyA signaling. We propose that FHY3 and FAR1 represent transcription factors that have been co-opted from an ancient Mutator-like transposase(s) to modulate phyA-signaling homeostasis in higher plants.

We next used a yeast one-hybrid assay to delineate the DNA sequences to which FHY3 and FAR1 bind. GAD-FHY3 or GAD-FAR1 fusion proteins (GAD, GAL4 transcriptional activation domain), but not GAD alone, activated the LacZ reporter genes driven by the FHY1 and FHL promoters. Deletion analysis narrowed down the FHY3/FAR1 binding site to a 39-bp promoter subfragment located on the "a" fragment for both FHY1 and FHL. Notably, these subfragments share a stretch of consensus sequence, 5'-TTCACGCGCC-3'. Mutating the core sequence "CACGCGC" of this motif (m2 and m3 for FHY1, m5 for FHL) abolished the reporter gene activation by both GAD-FHY3 and GAD-FAR1. Mutating the flanking sequences (m1 and m4) did not obviously affect the reporter gene activation by GAD-FAR1, but clearly reduced activation by GAD-FHY3. Thus, "CACGCGC" likely defines a cis-element that confers specific binding for FHY3 and FAR1 and is named FBS for FHY3-FAR1 binding site.

Lin R, Ding L, Casola C, Ripoll DR, Feschotte C, Wang H.
Transposase-derived transcription factors regulate light signaling in Arabidopsis.
Science, 2007. 318(5854): p. 1302-5.
PMID: 18033885