PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Daucus carota
bZIP Family
Species TF ID Description
DCAR_000690bZIP family protein
DCAR_001004bZIP family protein
DCAR_001125bZIP family protein
DCAR_001141bZIP family protein
DCAR_001450bZIP family protein
DCAR_001561bZIP family protein
DCAR_001701bZIP family protein
DCAR_001831bZIP family protein
DCAR_002023bZIP family protein
DCAR_002099bZIP family protein
DCAR_002896bZIP family protein
DCAR_002897bZIP family protein
DCAR_003095bZIP family protein
DCAR_003169bZIP family protein
DCAR_003659bZIP family protein
DCAR_003998bZIP family protein
DCAR_004268bZIP family protein
DCAR_004549bZIP family protein
DCAR_004782bZIP family protein
DCAR_005758bZIP family protein
DCAR_006160bZIP family protein
DCAR_006652bZIP family protein
DCAR_006686bZIP family protein
DCAR_006961bZIP family protein
DCAR_007210bZIP family protein
DCAR_007539bZIP family protein
DCAR_007751bZIP family protein
DCAR_008218bZIP family protein
DCAR_009107bZIP family protein
DCAR_009151bZIP family protein
DCAR_009159bZIP family protein
DCAR_009765bZIP family protein
DCAR_009857bZIP family protein
DCAR_009964bZIP family protein
DCAR_010092bZIP family protein
DCAR_010801bZIP family protein
DCAR_010997bZIP family protein
DCAR_011611bZIP family protein
DCAR_012190bZIP family protein
DCAR_012705bZIP family protein
DCAR_012720bZIP family protein
DCAR_012848bZIP family protein
DCAR_013173bZIP family protein
DCAR_013381bZIP family protein
DCAR_013520bZIP family protein
DCAR_013537bZIP family protein
DCAR_013560bZIP family protein
DCAR_013644bZIP family protein
DCAR_014251bZIP family protein
DCAR_014428bZIP family protein
DCAR_017231bZIP family protein
DCAR_017518bZIP family protein
DCAR_017622bZIP family protein
DCAR_019449bZIP family protein
DCAR_019806bZIP family protein
DCAR_019835bZIP family protein
DCAR_020060bZIP family protein
DCAR_020597bZIP family protein
DCAR_020616bZIP family protein
DCAR_020756bZIP family protein
DCAR_021009bZIP family protein
DCAR_021277bZIP family protein
DCAR_021480bZIP family protein
DCAR_021825bZIP family protein
DCAR_022020bZIP family protein
DCAR_022100bZIP family protein
DCAR_022457bZIP family protein
DCAR_022792bZIP family protein
DCAR_022810bZIP family protein
DCAR_022924bZIP family protein
DCAR_022938bZIP family protein
DCAR_023944bZIP family protein
DCAR_025821bZIP family protein
DCAR_025934bZIP family protein
DCAR_026693bZIP family protein
DCAR_028432bZIP family protein
DCAR_029264bZIP family protein
DCAR_029986bZIP family protein
DCAR_030068bZIP family protein
DCAR_030075bZIP family protein
DCAR_030415bZIP family protein
DCAR_030478bZIP family protein
DCAR_031809bZIP family protein
bZIP Family Introduction

The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.

Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Jakoby M, Weisshaar B, Droge-Laser W, Vicente-Carbajosa J, Tiedemann J, Kroj T, Parcy F
bZIP transcription factors in Arabidopsis.
Trends Plant Sci, 2002. 7(3): p. 106-11.
PMID: 11906833