PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Daucus carota
WRKY Family
Species TF ID Description
DCAR_000635WRKY family protein
DCAR_000809WRKY family protein
DCAR_001382WRKY family protein
DCAR_004233WRKY family protein
DCAR_004610WRKY family protein
DCAR_005034WRKY family protein
DCAR_005083WRKY family protein
DCAR_005143WRKY family protein
DCAR_005379WRKY family protein
DCAR_005574WRKY family protein
DCAR_005640WRKY family protein
DCAR_005753WRKY family protein
DCAR_005872WRKY family protein
DCAR_006949WRKY family protein
DCAR_007136WRKY family protein
DCAR_007177WRKY family protein
DCAR_007343WRKY family protein
DCAR_007815WRKY family protein
DCAR_008173WRKY family protein
DCAR_008352WRKY family protein
DCAR_008638WRKY family protein
DCAR_008655WRKY family protein
DCAR_009610WRKY family protein
DCAR_010624WRKY family protein
DCAR_010654WRKY family protein
DCAR_010862WRKY family protein
DCAR_012337WRKY family protein
DCAR_012521WRKY family protein
DCAR_012791WRKY family protein
DCAR_012904WRKY family protein
DCAR_013280WRKY family protein
DCAR_014229WRKY family protein
DCAR_014497WRKY family protein
DCAR_014683WRKY family protein
DCAR_014957WRKY family protein
DCAR_016302WRKY family protein
DCAR_016536WRKY family protein
DCAR_016808WRKY family protein
DCAR_017993WRKY family protein
DCAR_018041WRKY family protein
DCAR_018294WRKY family protein
DCAR_019232WRKY family protein
DCAR_019267WRKY family protein
DCAR_019421WRKY family protein
DCAR_019422WRKY family protein
DCAR_019758WRKY family protein
DCAR_019969WRKY family protein
DCAR_020141WRKY family protein
DCAR_020153WRKY family protein
DCAR_021163WRKY family protein
DCAR_021299WRKY family protein
DCAR_021802WRKY family protein
DCAR_021820WRKY family protein
DCAR_022855WRKY family protein
DCAR_023855WRKY family protein
DCAR_023971WRKY family protein
DCAR_024663WRKY family protein
DCAR_025398WRKY family protein
DCAR_025562WRKY family protein
DCAR_026069WRKY family protein
DCAR_026990WRKY family protein
DCAR_027713WRKY family protein
DCAR_027985WRKY family protein
DCAR_028753WRKY family protein
DCAR_028893WRKY family protein
DCAR_030029WRKY family protein
DCAR_030459WRKY family protein
DCAR_031047WRKY family protein
DCAR_032121WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701