PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Daucus carota
ARF Family
Species TF ID Description
DCAR_001722ARF family protein
DCAR_003884ARF family protein
DCAR_004039ARF family protein
DCAR_004816ARF family protein
DCAR_005400ARF family protein
DCAR_006053ARF family protein
DCAR_006434ARF family protein
DCAR_006517ARF family protein
DCAR_007870ARF family protein
DCAR_007988ARF family protein
DCAR_011930ARF family protein
DCAR_014129ARF family protein
DCAR_014278ARF family protein
DCAR_014788ARF family protein
DCAR_014984ARF family protein
DCAR_015554ARF family protein
DCAR_017496ARF family protein
DCAR_017703ARF family protein
DCAR_018803ARF family protein
DCAR_018826ARF family protein
DCAR_020464ARF family protein
DCAR_022437ARF family protein
DCAR_025262ARF family protein
DCAR_025655ARF family protein
DCAR_027886ARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969