PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Citrus sinensis
WOX Family
Species TF ID Description
orange1.1g039144mWOX family protein
orange1.1g027928mWOX family protein
orange1.1g046813mWOX family protein
orange1.1g043602mWOX family protein
orange1.1g036802mWOX family protein
orange1.1g036145mWOX family protein
orange1.1g035594mWOX family protein
orange1.1g046372mWOX family protein
orange1.1g047211mWOX family protein
orange1.1g023479mWOX family protein
orange1.1g022944mWOX family protein
orange1.1g022926mWOX family protein
orange1.1g022558mWOX family protein
orange1.1g022516mWOX family protein
orange1.1g031304mWOX family protein
orange1.1g027250mWOX family protein
orange1.1g027068mWOX family protein
orange1.1g026809mWOX family protein
orange1.1g028506mWOX family protein
WOX Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401

The WOX genes form a plant-specific subclade of the eukaryotic homeobox transcription factor superfamily, which is characterized by the presence of a conserved DNA-binding homeodomain. The analysis of WOX gene expression and function shows that WOX family members fulfill specialized functions in key developmental processes in plants, such as embryonic patterning, stem-cell maintenance and organ formation. These functions can be related to either promotion of cell division activity and/or prevention of premature cell differentiation.

van der Graaff E, Laux T, Rensing SA.
The WUS homeobox-containing (WOX) protein family.
Genome Biol, 2009. 10(12): p. 248.
PMID: 20067590