PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Coccomyxa subellipsoidea C-169
bZIP Family
Species TF ID Description
estExt_fgenesh1_pg.C_30132bZIP family protein
estExt_fgenesh1_pg.C_40271bZIP family protein
estExt_fgenesh1_pm.C_170068bZIP family protein
estExt_Genemark1.C_120280bZIP family protein
estExt_Genemark1.C_200086bZIP family protein
estExt_Genemark1.C_20115bZIP family protein
fgenesh1_kg.24_#_12_#_3604_1_CBOZ_CBPAbZIP family protein
fgenesh1_kg.2_#_60_#_3265_1_CBOZ_CBPAbZIP family protein
fgenesh1_kg.6_#_93_#_4895_0_CBOZ6187.b1_CBOZ_CBPAbZIP family protein
fgenesh1_pg.2_#_40bZIP family protein
fgenesh1_pg.3_#_171bZIP family protein
fgenesh1_pg.3_#_344bZIP family protein
fgenesh1_pg.6_#_173bZIP family protein
fgenesh1_pg.6_#_391bZIP family protein
fgenesh1_pg.7_#_208bZIP family protein
Genemark1.4306_gbZIP family protein
Genemark1.5055_gbZIP family protein
Genemark1.5498_gbZIP family protein
Genemark1.5722_gbZIP family protein
Genemark1.6261_gbZIP family protein
Genemark1.6443_gbZIP family protein
Genemark1.6723_gbZIP family protein
Genemark1.7971_gbZIP family protein
Genemark1.8412_gbZIP family protein
Genemark1.8628_gbZIP family protein
Genemark1.8632_gbZIP family protein
Genemark1.90_gbZIP family protein
bZIP Family Introduction

The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.

Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Jakoby M, Weisshaar B, Droge-Laser W, Vicente-Carbajosa J, Tiedemann J, Kroj T, Parcy F
bZIP transcription factors in Arabidopsis.
Trends Plant Sci, 2002. 7(3): p. 106-11.
PMID: 11906833