PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Cannabis sativa
bZIP Family
Species TF ID Description
PK00315.1bZIP family protein
PK00315.2bZIP family protein
PK00843.1bZIP family protein
PK01815.1bZIP family protein
PK02169.1bZIP family protein
PK02169.2bZIP family protein
PK03779.1bZIP family protein
PK05001.1bZIP family protein
PK05128.1bZIP family protein
PK05989.1bZIP family protein
PK05989.2bZIP family protein
PK06492.1bZIP family protein
PK07115.1bZIP family protein
PK07387.1bZIP family protein
PK07494.1bZIP family protein
PK07533.1bZIP family protein
PK08582.1bZIP family protein
PK08841.1bZIP family protein
PK08844.1bZIP family protein
PK09021.1bZIP family protein
PK09021.2bZIP family protein
PK09653.1bZIP family protein
PK09653.2bZIP family protein
PK09729.1bZIP family protein
PK09738.1bZIP family protein
PK09738.2bZIP family protein
PK09783.1bZIP family protein
PK10359.1bZIP family protein
PK11472.1bZIP family protein
PK11472.2bZIP family protein
PK11776.1bZIP family protein
PK13754.1bZIP family protein
PK14065.1bZIP family protein
PK14534.1bZIP family protein
PK14734.1bZIP family protein
PK16223.1bZIP family protein
PK16335.1bZIP family protein
PK16522.1bZIP family protein
PK17047.1bZIP family protein
PK17235.1bZIP family protein
PK18009.1bZIP family protein
PK18699.1bZIP family protein
PK19730.1bZIP family protein
PK20942.1bZIP family protein
PK21227.1bZIP family protein
PK21698.1bZIP family protein
PK22350.1bZIP family protein
PK23964.1bZIP family protein
PK24205.1bZIP family protein
PK24738.1bZIP family protein
PK24978.1bZIP family protein
PK26579.1bZIP family protein
PK27109.1bZIP family protein
PK27149.1bZIP family protein
bZIP Family Introduction

The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.

Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Jakoby M, Weisshaar B, Droge-Laser W, Vicente-Carbajosa J, Tiedemann J, Kroj T, Parcy F
bZIP transcription factors in Arabidopsis.
Trends Plant Sci, 2002. 7(3): p. 106-11.
PMID: 11906833