PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Cannabis sativa
ERF Family
Species TF ID Description
PK01156.1ERF family protein
PK01824.1ERF family protein
PK01935.1ERF family protein
PK02330.1ERF family protein
PK02602.1ERF family protein
PK02998.1ERF family protein
PK03025.1ERF family protein
PK04701.1ERF family protein
PK05014.1ERF family protein
PK05793.1ERF family protein
PK07402.1ERF family protein
PK07829.1ERF family protein
PK08321.1ERF family protein
PK08602.1ERF family protein
PK08949.1ERF family protein
PK09586.1ERF family protein
PK09781.1ERF family protein
PK11678.1ERF family protein
PK11782.1ERF family protein
PK12040.1ERF family protein
PK12109.1ERF family protein
PK13330.1ERF family protein
PK13470.1ERF family protein
PK15234.1ERF family protein
PK15554.1ERF family protein
PK15612.1ERF family protein
PK15705.1ERF family protein
PK16069.1ERF family protein
PK16401.1ERF family protein
PK16787.1ERF family protein
PK17878.1ERF family protein
PK18548.1ERF family protein
PK18885.1ERF family protein
PK19363.1ERF family protein
PK21096.1ERF family protein
PK22951.1ERF family protein
PK23186.1ERF family protein
PK23332.1ERF family protein
PK23512.1ERF family protein
PK24580.1ERF family protein
PK25211.1ERF family protein
PK25269.1ERF family protein
PK25715.1ERF family protein
PK25743.1ERF family protein
PK25970.1ERF family protein
PK26398.1ERF family protein
PK27421.1ERF family protein
PK27482.1ERF family protein
PK28082.1ERF family protein
PK28394.1ERF family protein
PK28640.1ERF family protein
PK28683.1ERF family protein
PK28774.1ERF family protein
PK28779.1ERF family protein
PK28823.1ERF family protein
PK29021.1ERF family protein
PK29047.1ERF family protein
PK29340.1ERF family protein
PK29475.1ERF family protein
ERF Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

After finding the tobacco ERFs, many proteins in the ERF family were identified and implicated in many diverse functions in cellular processes, such as hormonal signal transduction, response to biotic and abiotic stresses, regulation of metabolism, and in developmental processes in various plant species.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444


The first class are proteins which bind to ethylene response elements (ERE) or GCC boxes (tobacco EREBPs, Arabidopsis AtEBP and AtERF1-5, and tomato Pti4-6) found in the promoters of ethylene-inducible pathogenesis related genes. The GCC box is an 11 bp sequence (TAAGAGCCGCC) with a core GCCGCC sequence that is required for binding.
The second class includes proteins that bind to the C-repeat or dehydration response element (DRE) in the promoters of genes that are turned on in response to low temperatures and/or water deficit (CBF1, CBF2, CBF3/DREB1A and DREB2A). The C-repeat/DREs contain the core sequence CCGAC.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102