PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Capsella rubella
ARF Family
Species TF ID Description
Carubv10000065mARF family protein
Carubv10004139mARF family protein
Carubv10004220mARF family protein
Carubv10004222mARF family protein
Carubv10006513mARF family protein
Carubv10008159mARF family protein
Carubv10008165mARF family protein
Carubv10008239mARF family protein
Carubv10008258mARF family protein
Carubv10011010mARF family protein
Carubv10011321mARF family protein
Carubv10012424mARF family protein
Carubv10018954mARF family protein
Carubv10019454mARF family protein
Carubv10019991mARF family protein
Carubv10022415mARF family protein
Carubv10022755mARF family protein
Carubv10022841mARF family protein
Carubv10025185mARF family protein
Carubv10025860mARF family protein
Carubv10025912mARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969